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Diss Factsheets
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EC number: 203-636-9 | CAS number: 108-99-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
Type of Data
PBT-Criterion
vPvB-Criterion
Value for Substance
Conclusion
Persistence
Ready Biodegradability test (screening)
Not readily biodegradable
Not readily biodegradable
Readily biodegradable
Not P
Biodegradability by Simulation Testing (definitive)
t1/2> 60 days in marine water, or
t1/2> 40 days in fresh or estuarine water, or
t1/2> 60 days in marine, fresh- or estuarine water, or
t1/2> 180 days in marine sediment, or
t1/2> 180 days in marine, fresh- or estuarine sediment, or
t1/2> 120 days in soil
t1/2> 180 days in soil
Abiotic degradation
Photodegradation
Bioaccumulation
Evidence of biomagnification (definitive)
BCF > 2000 L/kg
BCF > 5000 L/kg
BCF = 2.6 (experimental); BCF – 2.876 (modeled)
Not B
Octanol-water partition coefficient (screening)
Log Kow> 4.5
Log Kow> 4.5
Log Kow= 1.2 (experimental)
Not B
Toxicity
Aquatic toxicity
Long-term NOEC < 0.01 mg/L (definitive); or short-term EC50or LC50< 0.01 mg/L (definitive); or short-term EC50or LC50< 0.1 mg/L (screening)
Short term EC50= 320 mg/L (daphnids); ErC50= 320 mg/L (algae)
Not T
Classified as carcinogenic (category 1A or 1B) , mutagenic (category 1 or 1B) or toxic to reproduction (category 1A ,1B or 2), according to the CLP Regulation; or
Not CMR
Not T
Evidence of chronic toxicity, i.e., specific target organ toxicity after repeated exposure (STOT RE category 1 or 2), according to the CLP regulation.
No chronic toxicity
Not T
Detailed information regarding the PBT/vPvB determination is summarised in the table (above). The substance has been shown to be readily biodegradable and therefore is not persistent. The substance has a log Kow of 1.2, below the screening criterion of 4.5, above which a substance may be considered to be bioaccumulative and very bioaccumulative; the substance has a a measured aquatic bioaccumulation factor of 2.6 and a predicted BCF of 2.876, each substantially below both the definitive BCF thresholds of 2000 L/kg for bioaccumulative and 5000 L/kg for very bioaccumulative. This substance does not meet the screening criteria for aquatic toxicity, as the lowest short-term L(E)C50value of 320 mg/L is substantially above the definitive criterion of L(E)C50< 0.01 mg/L and the screening criterion of L(E)C50< 0.1 mg/L. The substance does not meet any of the criteria for mammalian toxicity in accordance with the CLP Regulation, i.e., carcinogenic (category 1A or 1B), mutagenic (category 1 or 1B), toxic for reproduction (category 1A, 1B or 2), or other evidence of chronic toxicity, i.e., specific target organ toxicity after repeated exposure (STOT RE category 1 or 2). Thus, the substance has been determined to be not persistent, not bioaccumulative and not toxic, and is considered to be not PBT and not vPvB.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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