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EC number: 817-198-7 | CAS number: 1273322-47-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The lowest short-term result for Daphnia magna was found for oleylamine (Akzo Nobel, 1995). This study was conducted according to the OECD Guideline 202 (1984) in the presence or absence of humic acid with oleyl alkyl amine (purity 94%) as test substance. Daphnia were exposed to five test concentrations in the nominal concentration range between 0.006 and 0.09 mg/L in a static system for 48 h at a temperature of 19.1-19.7°C and a pH of 8.0-8.2. For the preparation of the stock dispersions (0.1 g/L) ultrasonic treatment was used and during each dosing step the stock solutions were stirred. At the start of the tests, all test solutions were clear and homogeneous. During all tests the test substance content (measured at 0 h and 48 h via HPLC) decreased strongly showing a wide spread of the recovery rates (test without humic acid: recovery 48-118%, mean value 81%; test with 10 mg/l humic acid: recovery 23-98%, mean value 56%; test with 20 mg/l humic acid: recovery 0-23%, mean value 7.4%). Due to this, no calculations based on measured concentrations were performed.
Based on nominal concentrations the 48h-EC50 values were calculated as 0.011 mg/L (without humic acid), 0.43 mg/L (10 mg/l humic acid) and 0.56 mg/l (20 mg/L humic acid). Compared to the test results without humic acid, the addition of 10 mg/L humic acid resulted in an approximate 40-fold higher EC50.
Additionally, studies using different species of invertebrates describing effects of pH, temperature and stage of insect development are reported for different primary fatty amines. An enhancement of toxicity of octylamine and decylamine on larval mortality of Elminius modestus at higher pH and lower temperature is described by Christie & Crisp (1966). Larvae of Culex pipiens quinquefasciatus are more sensitive to primary fatty amines than pupae (Mulla 1967 a, b) and Aedes aegypti (Cline 1972). Larvae and pupae of Anopheles sp. and Aedes sp. are of similar sensivity to oleylamine and coco alkyl amines (Mulla 1970).
Additional acute daphnia tests in natural river water (River Boehme) with a DOC of 6.3 mg/L and suspended matter of 16.7 mg/L (Noack, 2006) were carried out. The lowest 48h-EC50bulk of 0.32mg/l was derived for cocoamine.
In river water the Primary alkyl amines which are cationic surfactants at pH relevant in the environment, are either dissolved in water or sorbed to dissolved and particulate matter. No sorption to glass ware occurs under these conditions which were confirmed by measurements. This ensures reliable as well as reproducible results. Ecotoxicity is mitigated due to sorption but this kind of tests at least ensures that all added test substance is present in the test system and available for the exposure of the organism in dissolved or sorbed form. Mitigation can be taken into account by a factor of 10 applied to the ecotoxicty result for C&L. For risk assessment purposes these ecotoxicity results can be compared with the total or bulk concentration in surface water.
Additional Literature
Christie, A.O. & Crisp, D.J. (1966): Toxicity of aliphatic amines to barnacle larvae. Comp. Biochem. Physiol. (18), 59-69
Cline, R.E. (1972): Lethal effects of aqueous formulations containing fatty amines or acids against eggs and larvae of Aedes aegypti. J. Econ. Entomol. (65), 177-181
Mulla, M.S. (1967a): Biocidal and Biostatic Activity of Aliphatic Amines Against Southern House Mosquito Larvae and Pupae. J. Econ. Entomol. (60) 515-522
Mulla, M.S. (1967b): Biological activity of surfactants and some chemical intermediates against pre-imaginal mosquitoes. Proc. Pap. Annu. Conf. Calif. Mosquito Contr. Assoc. (35), 111-117
Mulla, M.S. (1970): Evaluation of aliphatic amines against larvae and pupae of mosquitoes. J. Econ. Entomol. (63), 1472-1475
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.32 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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