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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1971

Materials and methods

Principles of method if other than guideline:
10 male albino Wistar rats per dose. 16 hour predose fast. 14 day observation period
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
α,α-dimethylphenethyl acetate
EC Number:
205-781-3
EC Name:
α,α-dimethylphenethyl acetate
Cas Number:
151-05-3
Molecular formula:
C12H16O2
IUPAC Name:
1,1-dimethyl-2-phenylethyl acetate
Test material form:
solid

Test animals

Species:
rat
Strain:
Wistar
Sex:
male

Results and discussion

Effect levels
Key result
Sex:
male
Dose descriptor:
LD50
Effect level:
ca. 3.3 other: g/kg
95% CL:
>= 2.55 - <= 4.05

Applicant's summary and conclusion