Registration Dossier
Registration Dossier
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EC number: 924-168-8 | CAS number: 92128-66-0
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Hazard for air
Hazard for terrestrial organisms
Hazard for predators
Additional information
No studies are available on the acute toxicity for hydrocarbons, C6-C7, n-alkanes, isoalkanes, cyclics, > 5% n-hexane. Based on a category approach data are read-across to hydrocarbons, C6-C7, n-alkanes, isoalkanes, cyclics, <5% n-hexane. The ecotoxicity of hydrocarbons, C6-C7, n-alkanes, isoalkanes, cyclics, <5% n-hexane has been examined in a series of studies on fish, Daphnia and algae, and additional QSAR modelling has been performed. The most conservative results of aquatic studies showed this substance to be of moderate toxicity, with LL50 or EL50 values of 3 mg/L (Daphnia), 11.4 mg/L (fish), and 10 mg/L (algae). All of these studies were conducted in Water Accomodated Fraction (WAF) studies because of the limited water solubility. QSAR modelling data on microorganisms resulted in an EL50 of 35.29 mg/L. One study in the category is available on chronic aquatic toxicity for Daphnia with a NOELR of 1 mg/L. QSAR modelling was performed to address chronic toxicity of hydrocarbons, C6-C7, n-alkanes, isoalkanes, cyclics, <5% n-hexane and a NOELR was estimated as 2.028 mg/L for fish. Standard tests for terrestrial endpoints are intended for single substances and are not appropriate for the risk assessment of this complex substance. For the purpose of risk assessment, soil PNECs for hydrocarbon blocks have been derived using aquatic PNECs and the equilibrium partitioning method (EqP) using representative structures. Studies on long-term or reproductive toxicity to birds do not need to be conducted due to the existence of a large mammalian dataset demonstrating low toxicity to higher organisms.
Conclusion on classification
The substance is readily biodegradable. The most sensitive acute aquatic value is an EL50 of 3 mg/L (Daphnia). Measured data on BCF and the log Kow are not available. An evaluation of representative hydrocarbon structures using the PETRORISK model indicates no structures meet the Bioaccumulative (B) or very Bioaccumulative (vB) criteria. Chronic toxicity values are 1 mg/L (read-across, experimental result). Log Kow values are available for compounds (see Product Library in PETRORISK spreadsheet attached in IUCLID section 13).The substance is classified aquatic chronic category 2 according to CLP/GHS and classified R 51/53 according to DSD/DPD.
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