N-benzyl-N-ethylaniline

Toxicity to microorganisms

Link to relevant study record(s)

Reference

Endpoint:

toxicity to microorganisms, other

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

secondary literature

Justification for type of information:

Data is from secondary source Advisory Board for Environmentally Relevant Existing Substances (BUA)

Qualifier:

according to guideline

Guideline:

other: refer below principle

Principles of method if other than guideline:

Ecotoxicological study was evaluate for chemical for 96 hrs.

GLP compliance:

not specified

Analytical monitoring:

not specified

Vehicle:

not specified

Test organisms (species):

Escherichia coli

Test type:

not specified

Water media type:

freshwater

Total exposure duration:

96 h

Reference substance (positive control):

not specified

Key result

Duration:

96 h

Dose descriptor:

EC0

Effect conc.:

50 mg/L

Nominal / measured:

not specified

Conc. based on:

test mat.

Basis for effect:

not specified

Validity criteria fulfilled:

not specified

Conclusions:

From authorative data source the effect concentration (EC0) for bacteria Escherichia coli was observed to be 50 mg/l for 96 hrs exposure period.

Executive summary:

In Advisory Board for Environmentally Relevant Existing Substances (BUA);2000 report the ecotoxicological and toxicological aspect of chemical was studied.

According to report the effect concentration (EC0) for bacteria Escherichia coli was observed to be 50 mg/l for 96 hrs exposure period. Based on the effect concentration it may considered that the test chemical may have aquatic toxicity concern to micro organism at higher dose concentrations for acute exposure.

Description of key information

In Advisory Board for Environmentally Relevant Existing Substances (BUA);2000 report the ecotoxicological and toxicological aspect of chemical N-Benzyl-N-ethylaniline (BEA) was studied.According to report the effect concentration (EC0) for bacteria Escherichia coli was observed to be 50 mg/l for 96 hrs exposure period.Based on the effect concentration it may considered that the test chemical N-Benzyl-N-ethylaniline (BEA) may have aquatic toxicity concern to micro organism at higher dose concentrations for acute exposure.

Additional information

Two studies including experimental data from peer reviewed journal and authorative database for toxicity to micro organism endpoint of test chemical N-benzyl-N-ethylaniline (Cas no. 92-59-1) with relevant read across which is close to target by structure were summarised as follows:

First study of target from secondary source Advisory Board for Environmentally Relevant Existing Substances (BUA) which suggests the ecotoxicological and toxicological aspect of chemical N-Benzyl-N-ethylaniline (BEA) was studied and according to report the effect concentration (EC0) for bacteria Escherichia coli was observed to be 50 mg/l for 96 hrs exposure period.Based on the effect concentration it may considered that the test chemical N-Benzyl-N-ethylaniline (BEA) may have aquatic toxicity concern to micro organism at higher dose concentrations for acute exposure.

And peer reviewed journal Toxicology methods, 7, 289-309; 1997 for read across chemical N,N-diethylaniline (Cas no.91 -66 -7) indicate the 50 percent growth impairment concentration (IGC 50) of N,N-diethylaniline in the micro-organism Tetrahymena pyriformis during a 48 hr study was reported as 0.67mg/L.The observed growth impairment concentration suggest that the chemical N,N-diethylaniline (Cas no.91 -66 -7) may have concern to toxicity to micro organism for acute exposure period.

Both experimental study of toxicity to micro organism give the conclusion that the test chemical N-benzyl-N-ethylaniline (Cas no. 92-59-1) may have toxicity concern for acute exposure.