Registration Dossier
Registration Dossier
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EC number: 217-978-1 | CAS number: 2028-63-9
Endpoint summary
Administrative data
Description of key information
Biodegradation in water: screening test
Based on the rate of biodegradation of 30-40 % CO2/ThCO2 at the end of exposure the test substance can be evaluated as moderately or partly biodegradable in this test.
Additional information
Biodegradation in water: screening test
Key study
In the GLP and OECD 301 B guideline compliant ready biodegradability study the test substance (57% solution) was tested for ready biodegradability.
The test substance was not readily biodegradable in this carbon dioxide evolution test based on the quantitative determination of the formed carbon dioxide in the test substance assays by comparison with the calculated maximal theoretical carbon dioxide production.
The required pass level for ready biodegradability within a ten days window was not reached.
The degree of biodegradation after an exposure period of 28 days was 30-40 % CO2/ThCO2 in this test. The degree of biodegradation was calculated as mean of the values from two test assays at the end of exposure.
Based on the rate of biodegradation of 30-40 % CO2/ThCO2 at the end of exposure the test substance can be evaluated as moderately or partly biodegradable in this test.
The results in this study are consistent with all relevant validity criteria and the test is valid according to the test guideline of this study. No deviations from the test guidelines or other incidents occurred during the course of the reported test, which may have influenced the results.
Supporting study
The ready biodegradability of the test substance (55 % solution) was determined according to DIN 38409 Part 43 based on the determination of biochemical oxygen demand. At the end of the test, the test was biodegraded by an average of < 1 %, therefore the test substance was found to be not ready biodegradable under the test conditions.
In addition a non GLP study according to the OECD guideline 302 B (Inherent biodegradability: Zahn-Wellens Test) with the test substance has also been performed. The biodegradation of the test substance was followed by exposing it to the adapted activated sludge from industrial waste water treatment plant over 28 days. Under the OECD conditions the test item was degraded > 70 % after 28 days, therefore the test substance is considered to be not ready but inherently biodegradable.
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