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EC number: 294-268-8 | CAS number: 91697-07-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
read across to the stuctural very similar substance Sulfosuccinic (FA C12-18)E, 2Na.
The 96‑hour LC50of Sulfosuccinic (FA C12-18)E, 2Na was deviated to be 2.0 mg/L.
The results of this study are considered relevant and reliable for the risk assessment.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 2 mg/L
Additional information
No fish study (OECD 203) is available for the registered substance. The data gap, however, is brigded by read across to the stuctural very similar substance Sulfosuccinic (FA C12-18)E, 2Na.
In the Klimisch 1 GLP study from Kimmel (2013) (read across study) the acute toxicity of Sulfosuccinic (FA C12-18)E, 2Na to zebra fish (Danio rerio) was determined in a 96‑hour semi-static test with daily test medium renewal according to the EU Commission Directive 92/69/, Part C.1, the Commission Regulation (EC) No 440/2008, Part C.1 and the OECD Guideline for Testing of Chemicals No. 203 (1992). The following nominal concentrations were tested: 0.15, 0.47, 1.5, 4.7 and 15 mg/L mg test item/L. Additionally, a control (test water without test item) was tested in parallel.
The measured concentrations of the test item in the test media of the test concentrations of 0.15 to 15 mg/L were between 81 and 112% of the nominal values at the start of the test and below Limit of Quantification (LOQ) to 109% at the end of each renewal period. Thus, the correct dosage of the test item was confirmed, but the test item concentrations of the two lowest concentrations declined below 80% over the renewal period of 24 hours. Therefore the biological results were related to the following mean measured test item concentrations: control, 0.090, 0.33, 1.6, 4.8 and 16 mg test item/L.
In the control and at the test concentrations up to and including 0.090 mg/L, all fish survived until the end of the test and no visible abnormalities were observed in the test fish. At the next higher test concentration of 0.33 mg/L, three test fish showed one or several visible abnormalities. One of the seven test fish died at this test concentration. At the test concentration of 4.8 mg/L all test fish were dead after 48 hours of test duration while at the highest test concentration of 16 mg/L, all fish were dead already after 24 hours of test duration. Thus, the 96‑hour NOEC and LC0of Sulfosuccinic (FA C12-18)E, 2Na to zebra fish were both determined to be 0.090 mg/L. The 96‑hour LC50of Sulfosuccinic (FA C12-18)E, 2Na was calculated to be 2.0 mg/L with a 95% confidence interval of 0.8-3.3 mg/L. The 96‑hour LC100was 4.8 mg/L.
The results of this study are considered relevant and reliable for the risk assessment.
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