Registration Dossier
Registration Dossier
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EC number: 800-036-4 | CAS number: 1422423-64-0
Endpoint summary
Administrative data
Description of key information
Fish EC50 (96h) > 100 mg/l (nominal)
Invertebrates EC50 (48h) > 100 mg/l (nominal)
Algae ErC50 (72h) > 100 mg/l (nominal)
Microorganisms EC50 (3h) > 1000 mg/l (nominal)
Additional information
The evaluation of the aquatic toxicity of the target substance is based on experimental results conducted on the substance in itself; the studies have been conducted using organisms that represent three trophic levels. Below, the results of the experimental procedures are summarized.
Abiotic degradation can be considered as negligible at pH conditions of aquatic toxicity tests. Althoughtthe substance is readily biodegradable, it can be expected to be stable for the experimental periods characteristics of the assays performed on fish, invertebrates and algae.
The concentration of test item was measured by HPLC at the beginning of the test and after 2, 24, 48, 72 and 96 h of exposure, in the short-term toxicity to fish experiment and it was shown that the concentration could satisfactorily maintained over the 96 h test period.
In conclusion, the nominal concentration can be used for the assessment.
Short-term toxicity to fish
The acute toxicity to fish was investigated under semi-static exposure conditions over a period of 96 h, according to the OECD Guideline 203 by means of a limit test (100 mg/l nominal).
At the nominal concentration of 100 mg/l of test substance, after 96 hours, no deaths occurred.
EC50 (96h) > 100 mg/l (nominal)
Short-term toxicity to aquatic invertebrates
The acute toxicity to invertebrates was determined on Daphnids in a 48‑hour static limit test (100 mg/l) according to the OECD Guideline 202.
No significant mortality was observed in the test medium after 24 and 48 hours (Fisher's Exact test).
EC50 (48h) > 100 mg/l (nominal)
Toxicity to aquatic algae and cyanobacteria
The toxicity to aquatic algae was investigated on the Selenastrum capricornutum, in a 72-hour full test according to the OECD Guideline 201.
ErC50 (72h) > 100 mg/l (nominal)
EyC50 (72h) = 65.66 mg/l (nominal)
Toxicity to microorganisms
The inhibitory effect on the oxygen consumption of activated sludge microorganisms of a municipal sewage treatment plant was investigated according to the OECD Guideline 209 under aerobic static conditions over an exposure time of 3 hours.
No significant inhibition of the activated sludge respiration, as compared to the untreated controls, was observed at any of the four concentrations tested.
EC50 (3h) > 1000 mg/l (nominal)
NOEC (3h) ≥ 1000 mg/l (nominal)
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