Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 227-022-5 | CAS number: 5601-29-6
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Only short abstract available
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 1 990
- Report date:
- 1990
Materials and methods
- Principles of method if other than guideline:
- No available information on the method used
- GLP compliance:
- not specified
- Test type:
- other: no data
- Limit test:
- yes
Test material
- Reference substance name:
- Acid Yellow 059
- IUPAC Name:
- Acid Yellow 059
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- male
- Details on test animals or test system and environmental conditions:
- - Weight at study initiation: 220 - 260 g
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- not specified
- Doses:
- 5000 mg/kg bw
- No. of animals per sex per dose:
- 5 animals
- Control animals:
- not specified
Results and discussion
Effect levelsopen allclose all
- Sex:
- male
- Dose descriptor:
- LD50
- Effect level:
- > 5 000 mg/kg bw
- Based on:
- not specified
- Sex:
- male
- Dose descriptor:
- LD0
- Effect level:
- < 5 000 mg/kg bw
- Based on:
- not specified
- Mortality:
- No death occurred
- Clinical signs:
- other: No effects observed
- Gross pathology:
- No macroscopic changes observed
Any other information on results incl. tables
No other information is available
Applicant's summary and conclusion
- Interpretation of results:
- other: CLP Criteria not met
- Conclusions:
- LD50 > 5000 mg/kg bw
- Executive summary:
Method
No information is available on the method used. Only a short abstract is available. A limit test has been conducted on male wistar rats.
Observations
No clinical signs have been observed. At necroscopy no macroscopic changes have been observed.
Results
No death occurred, LD50 > 5000 mg/kg bw
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
