Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 215-202-6 | CAS number: 1313-13-9
Carcinogenicity
Administrative data
Description of key information
No reliable standard study is available for carcinogenicity.
Key value for chemical safety assessment
Carcinogenicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Carcinogenicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Carcinogenicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
No reliable standard study is available for carcinogenicity.
Based on data reported by Furst, 1988 about a mixture of manganese dioxide and manganese powder there is reasonably no concern about carcinogenicity of manganese dioxide.
MnO2 is not classified for Carcinogenicity according to annex VI of CLP Regulation (EC n.1272/2008).
Additional information
No reliable standard study is available for carcinogenicity.
No carcinogenicity were observed after intramuscular injection and oral administration of a suspensions of manganese dioxide and manganese powder into F344 rats and Swiss albino mice (see Furst, Tumorigenic effect of an organomanganese compound on F344 rats and Swiss albino mice, Journal of NationalCancer Institute, 60(5): 1171-1173, 1978 mentioned in SIDS Dossier of MnO2 approved at SIAM 25 (17 -18 October 2007)).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
