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EC number: 440-930-8 | CAS number: 330198-48-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- July 19, 2001 till August 08, 2001
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study according to OECD Guideline 105 (Water Solubility) under GLP
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 002
- Report date:
- 2002
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- column elution method
Test material
- Reference substance name:
- ZP-TIX 1014
- IUPAC Name:
- ZP-TIX 1014
- Details on test material:
- Identity: ZP-TIX 1014
Batch: NW-01-028
Purity > 99%,
Appearance: Solid
Expiration date: 30.12.2001
Storage: At room temperature at about 20°C
The test item consits of three components. For the quantification the peak area sum of these three components was used.
Constituent 1
Results and discussion
Water solubility
- Water solubility:
- < 0.9 mg/L
- Temp.:
- 20 °C
- pH:
- ca. 7
- Details on results:
- During the preliminary test the water solubility of ZP-TIX 1014 at room temperature was estimated by a simplified flask method to be lower than the smallest calibration point of 0.9436µg/ml. Therefore, the column elution method was used for the performance of the main test.
During the main test six samples have been analysed in the first run (0.52 ml/min) and six samples during the second run (0.26 ml/min), each with a sampling intervalof one hour. Total elution time was 97.5 hours. The quantification was performed by HPLC. The measured results differ by less than 30%. Therefore the sutdy is considered to be valid.
The test item could not be detected in any of the eluated samples.
In conclusion, the water solubility of ZP-TIX 1014 at 20°C +/- 0.5 °C was determined to be below the smallest calibration point which is < 0.9 mg/l.
Any other information on results incl. tables
Experiment No. | Flow rate [ml/h] | Sample No. | Concentration analysed [µg/ml] | Water solubility calculated [mg/l] | pH |
1 | 31 | 1 | < 0.9436 | < 0.9436 * | 7 |
2 | < 0.9436 | 7 | |||
3 | < 0.9436 | 7 | |||
4 | < 0.9436 | 7 | |||
5 | < 0.9436 | 7 | |||
6 | < 0.9436 | 7 | |||
2 | 16 | 7 | < 0.9436 | 7 | |
8 | < 0.9436 | 7 | |||
9 | < 0.9436 | 7 | |||
10 | < 0.9436 | 7 | |||
11 | < 0.9436 | 7 | |||
12 | < 0.9436 | 7 |
* The measured concentration is below the smalles calibration point of 0.9436 mg/ ml
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
In conclusion, the water solubility of ZP-TIX 1014 at 20°C ± 0.5 °C was determined to be below the smallest calibration point which is < 0.9 mg/L using the column elution method. - Executive summary:
The determination of the water solubility of ZP- TIX 1014 was performed according to the EEC Directive 92/69, A.6 'Water Solubility" (1992) and the OECD guideline No. 105, 'Water Solubility" (adopted July 27, 1995).
During the preliminary test the water solubility of ZP- TIX 1014 at room temperature was estimated by a simplified flask method to be lower than the smallest calibration point of 0.9436 pg/mL. Therefore, the column elution method was used for the performance of the main test.
During the main test six samples have been analysed in the first run (0.52 mL/min) and six samples during the second run (0.26 mL/min), each with a sampling interval of one hour. Total elution time was 97.5 hours. The quantification was performed by HPLC. The measured results differ by less than 30 %. Therefore the study is considered to be valid.
The test item could not be detected in any of the eluate samples.
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