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EC number: 231-634-8 | CAS number: 7664-39-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to soil microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to soil microorganisms
- Type of information:
- other: review
- Adequacy of study:
- key study
- Study period:
- 24 to 63 days
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Remarks:
- Recent review of published work on fluoride ions. Methodologcial data for individual studies are incomplete, however the studies have been assessed as part of the EU RAR and are therefore considered to be suitably reliable.
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The EU RAR summarises the results of a number of relevant studies
- GLP compliance:
- no
- Specific details on test material used for the study:
- Not relevant
- Analytical monitoring:
- not specified
- Details on sampling:
- No details of sampling given in review.
- Vehicle:
- no
- Details on preparation and application of test substrate:
- No details on preparation and application of test substance given in the review.
- Test organisms (inoculum):
- soil
- Total exposure duration:
- 63 d
- Test temperature:
- Not stated
- Moisture:
- Not stated.
- Details on test conditions:
- No further details given in review
- Nominal and measured concentrations:
- not stated
- Reference substance (positive control):
- no
- Duration:
- 24 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 3 000 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: Dehydrogenase inhibition
- Remarks on result:
- other: sodium fluoride
- Remarks:
- (Rogers and Li, 1985)
- Duration:
- 63 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 340 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: NH4-minerilisation
- Remarks on result:
- other: potassium fluoride
- Remarks:
- (Van Wensem and Adema, 1991)
- Duration:
- 63 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 106 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: NO3-mineralisation
- Remarks on result:
- other: potassium fluoride
- Remarks:
- (Van Wensem and Adema, 1991)
- Duration:
- 63 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 1 060 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: P-mineralisation
- Remarks on result:
- other: potassium fluoride
- Remarks:
- (Van Wensem and Adema, 1991)
- Details on results:
- The NOEC values detailed in the report range from 106 to 3000 mg/kg. The 63 day experiments were carried out in a micro-ecosystem containing poplar litter (30% o.m) and the isopod Porcellio scaber Latr. Nitrification was found to be the most sensitive in the micro-ecosystem test.
- Results with reference substance (positive control):
- Not applicable
- Reported statistics and error estimates:
- Not applicable
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The NOEC values detailed in the report range from 106 to 3000 mg/kg. The 63 d experiments were carried out in a micro-ecosystem containing poplar litter (30% o.m) and the isopod Porcellio scaber Latr. Nitrification was found to be the most sensitive in the micro-ecosystem test.
- Executive summary:
The EU RAR reports NOEC values from 106 to 3000 mg/kg. The 63 day experiments were carried out in a micro-ecosystem containing poplar litter (30% o.m) and the isopod Porcellio scaber. Nitrification was found to be the most sensitive endpoint investigated in the micro-ecosystem test.
- Endpoint:
- toxicity to soil microorganisms
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- It is considered appropriate to address the toxicity to soil microorganisms data requirement for hydrogen fluoride (HF) by read-across to available data on sodium fluoride (NaF) and potassium fluoride (KF).
In water, HF dissociates rapidly to form hydrogen (H+) and fluoride (F−) ions, whereas NaF and KF rapidly dissociate to F- ions and their respective counter ion (i.e. Na+ and K+, respectively). Therefore, HF, NaF and KF (as well as other fluorides) will dissociate rapidly to form F- ions in the environment (including moist soil), with any effects observed being directly attributable to the F- ion. The Na+ and K+ ions are naturally occurring and regulated by organisms (i.e. by homeostatic mechanisms) and consequently is not considered to have an impact on the read-across of ecotoxicological data. On this basis, the profile of HF is comparable to that of NaF and KF with respect to the environment. - Reason / purpose for cross-reference:
- read-across source
- Duration:
- 24 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 3 000 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: Dehydrogenase inhibition
- Remarks on result:
- other: sodium fluoride
- Remarks:
- (Rogers and Li, 1985)
- Duration:
- 63 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 340 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: NH4-minerilisation
- Remarks on result:
- other: potassium fluoride
- Remarks:
- (Van Wensem and Adema, 1991)
- Duration:
- 63 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 106 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: NO3-mineralisation
- Remarks on result:
- other: potassium fluoride
- Remarks:
- (Van Wensem and Adema, 1991)
- Duration:
- 63 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 1 060 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: P-mineralisation
- Remarks on result:
- other: potassium fluoride
- Remarks:
- (Van Wensem and Adema, 1991)
- Details on results:
- The NOEC values detailed in the report range from 106 to 3000 mg/kg. The 63 day experiments were carried out in a micro-ecosystem containing poplar litter (30% o.m) and the isopod Porcellio scaber Latr. Nitrification was found to be the most sensitive in the micro-ecosystem test.
- Results with reference substance (positive control):
- Not applicable
- Reported statistics and error estimates:
- Not applicable
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The NOEC values detailed in the report range from 106 to 3000 mg/kg. The 63 d experiments were carried out in a micro-ecosystem containing poplar litter (30% o.m) and the isopod Porcellio scaber Latr. Nitrification was found to be the most sensitive in the micro-ecosystem test.
- Executive summary:
It is considered appropriate to address the toxicity to soil microorganisms data requirement for hydrogen fluoride (HF) by read-across to available data on sodium fluoride (NaF) and potassium fluoride (KF). In water, HF dissociates rapidly to form hydrogen (H+) and fluoride (F−) ions, whereas NaF and KF rapidly dissociate to F-ions and their respective counter ion (i.e. Na+and K+, respectively). Therefore, HF, NaF and KF (as well as other fluorides) will dissociate rapidly to form F- ions in the environment (including moist soil), with any effects observed being directly attributable to the F-ion. The Na+ and K+ ions are naturally occurring and regulated by organisms (i.e. by homeostatic mechanisms) and consequently is not considered to have an impact on the read-across of ecotoxicological data. On this basis, the profile of HF is comparable to that of NaF and KF with respect to the environment.
The EU RAR reports NOEC values from 106 to 3000 mg/kg. The 63 day experiments were carried out in a micro-ecosystem containing poplar litter (30% o.m) and the isopod Porcellio scaber. Nitrification was found to be the most sensitive endpoint investigated in the micro-ecosystem test.
Referenceopen allclose all
The NOEC values detailed in the report range from 106 to 3000 mg/kg. The 63 d experiments were carried out in a micro-ecosystem containing poplar litter (30% o.m) and the isopod Porcellio scaber. Nitrification was found to be the most sensitive in the micro-ecosystem test.
The NOEC values detailed in the report range from 106 to 3000 mg/kg. The 63 d experiments were carried out in a micro-ecosystem containing poplar litter (30% o.m) and the isopod Porcellio scaber. Nitrification was found to be the most sensitive in the micro-ecosystem test.
Description of key information
A number of studies are summarised and reveiwed in the EU RAR.
Key value for chemical safety assessment
- Long-term EC10 or NOEC for soil microorganisms:
- 106 mg/kg soil dw
Additional information
The EU RAR reports NOEC values from 106 to 3000 mg/kg. The 63 day experiments were carried out in a micro-ecosystem containing poplar litter (30% o.m) and the isopod Porcellio scaber Latr. Nitrification was found to be the most sensitive endpoint investigated in the micro-ecosystem test.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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