Registration Dossier
Registration Dossier
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EC number: 217-007-1 | CAS number: 1719-58-0
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
72-h EC50 >684 mg/l and NOEC 44 mg/l, S. capricornutum (read-across from CAS 1066-40-6).
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 684 mg/L
- EC10 or NOEC for freshwater algae:
- 44 mg/L
Additional information
No data are available for chlorodimethyl(vinyl)silane (CAS 1719-58-0). In water, chlorodimethyl(vinyl)silane hydrolyses very rapidly to dimethyl(vinyl)silanol, therefore good quality data for an appropriate structural analogue of this silanol, trimethylsilanol (CAS 1066-40-6), have been read across. The other hydrolysis product is hydrogen chloride.
A 72-hour EC50value of >684 mg/l and NOEC of 44 mg/l have been determined for the effects of trimethylsilanol on growth rate of Selenastrum capricornutum (new name: Pseudokirchneriella subcapitata) based on geometric mean measured concentrations of the test substance. This study is considered to be reliability 1 (reliable without restrictions); the read across of the results is considered to be reliability 2 (reliable with restrictions).
The potential for toxicity caused by the vinyl group has also been considered. Data for trimethoxyvinylsilane (CAS 2768-02-7) indicate that the vinyl fraction of the registered substance is of very low short-term toxicity to algae (7-d EC50 210 mg/l).
Refer to the discussion in the Section 6 endpoint summary for further discussion of the approach to chemical safety assessment for this registration substance, and justification for read-across used.
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