Registration Dossier
Registration Dossier
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EC number: 201-187-3 | CAS number: 79-22-1
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Hydrolysate of methyl chloroformate (Methanol, HCl, CO2): The inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriately low concentrations.
Key value for chemical safety assessment
Additional information
The hydrolysate (3 -d hydrolysis) of methyl chloroformate was tested in a GLP study following OECD TG 209. The EC50 (30 min) was determined to be > 1000 mg/L, related to nominal concentrations of the parent compound (BASF AG, 1999).
Hydrolysis product methanol: In a respiration inhibition test with activated sludge following OECD TG 209, the 3 -h EC50 was determined to be > 1000 mg/L (Kleĉka et al., 1985).
Species |
Results |
Remarks |
Reference |
Activated sludge, domestic |
EC50 (30 min) > 1000 mg/L (nominal), OECD TG 209 |
Hydrolysate (3 -d; Methanol, HCl, CO2); reliability: 1, key study |
BASF AG, 1999 |
Activated sludge, domestic |
EC50 (3 h) > 1000 mg/L (nominal); OECD 209 respiration inhibition test |
Hydrolysis product methanol; reliability: 2, key study |
Kleĉka et al., 1985 |
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