Registration Dossier
Registration Dossier
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EC number: 210-871-0 | CAS number: 624-92-0
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
- Freshwater species
Acute toxicity to Daphnia magna has been investigated through EPA OPPTS 850.1010, OECD Guideline 202 and EU Method C.2 (Acute Toxicity for Daphnia). Daphnia magna were exposed for 48 hours to an aqueous solution of dimethyl disulfide TC at different nominal concentrations of 0.970 - 2.13 - 4.70 - 10.3 - 22.7 and 50 mg/L. EC 50 - 48h determined is of 1.82 mg/L and NOEC - 48h is 0.618 mg/L (Noack M, 2007).
In another test, Daphnia magna were exposed for 48 hours to an aqueous solution of dimethyl disulfide at different nominal concentrations of 3.3 - 4.0 - 4.8 - 5.8 - 6.9 - 8.3 - 10.0 - 12.0 and 14.4 mg/L. EC 50 - 48h determined is of 7.0 mg/L and EC50 - 24h is of 13.4 mg/L (Thiebaud, 1996).
The results obtained (EC50 -48h of 7.0 and 1.82 mg/L) confirm that DMDS is toxic to freshwater invertebrates.
- Marine species
Acute toxicity to Saltwater Mysid (Americamysis bahia) has been investigated through EPA OPPTS 850.1035, ASTM Standard E729-96 and U.S. Environmental Protection Agency, Standard Evaluation Procedure: Acute Toxicity Test for Estuarine and Marine Organisms. Americamysis bahia were exposed for 96 hours to an aqueous solution of dimethyl disulfide at different nominal concentrations of 1.1 - 2.3 - 4.5 - 9.0 and 18 mg active ingredients (a.i.)/L. LC 50 - 96h determined is of 5 mg/L and NOEC - 96h is of 2.5 mg/L (Minderhout T. et al., 2007).
Acute toxicity has also been investigated for Eastern oyster. Crassostrea virginica were exposed for 96 hours to an aqueous solution of dimethyl disulfide at different nominal concentrations of 3.8 - 7.5 - 15 - 30 and 60 mg active ingredients (a.i.)/L. EC 50 - 96h determined is of 14 mg/L and NOEC - 96h is of 3 mg/L (Minderhout T. et al., 2007).
Those results also demonstrate that DMDS is toxic to marine invertebrates.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Dose descriptor:
- EC50
- Effect concentration:
- 1.82 mg/L
Marine water invertebrates
Marine water invertebrates
- Dose descriptor:
- EC50
- Effect concentration:
- 5 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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