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EC number: 233-971-6 | CAS number: 10476-85-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Strontium chloride is not skin irritant but damaging to the eyes which is a strontium ion related effect.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
Read across from Sr(NO3)2 to SrCl2 is envisaged and fully justified since possible effects occurred during testing could be regarded as strontium ion related effects. Furthermore, both substances (SrCl2 and Sr(NO3)2) are "very soluble" (above 10 g/L at 20°C) in water.
Justification for selection of skin irritation / corrosion endpoint:
The study performed by Allen (1997) is used as key study since the study is an in vivo study performed with strontium chloride which fulfills the requirements of regulation (EC) 1907/2006. Whereas, the study performed by Verbaan (2010) is an in vitro study and strontium nitrate was used as test substance. This study is only used as supportive information.
Justification for selection of eye irritation endpoint:
Only one study available.
Effects on eye irritation: corrosive
Justification for classification or non-classification
Skin
irritation:
Reference
Allen (1997) is considered as the key studies for in vivo skin
irritation and will be used for classification. The overall irritation
result is as follows:
Erythema & edema score:0 (in all animals at 24, 48 and 72h)
The classification criteria according to regulation (EC) 1272/2008 as irritating to skin are not met since no effects were observed, hence no classification required.
Eye irritation:
Reference Stitzinger (2010) is considered as the key study for eye irritation and will be used for classification. The overall irritation results are as follows:
Cornea score: 0 (in all animals at 24, 48 and 72h);
Iris score: 0 (in all animals at 24, 48 and 72h); Conjunctivae score: 2 (in all animals at 24, 48 and 72h); Chemosis score: max. 2 (in all animals).
The conjunctiva irritation observed in two animals was not fully reversible within 21 days. Therefore the substance has to be classified as eye damage substance and should be labelled with H318: Causes serious eye damage
Respiratory irritation:
The classification as respiratory irritant is covered under the endpoint specific target organ toxicity- single exposure and repeated exposure. Please refer to the endpoint summaries on acute toxicity (endpoint 7.2) and repeated dose toxicity (endpoint 7.5) for further information.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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