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EC number: 215-960-8 | CAS number: 1461-25-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 30 June 2004 to 21 August 2004
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Key result
- Water solubility:
- <= 0 g/L
- Temp.:
- 20 °C
- pH:
- 5.4 - 5.5
- Details on results:
- Recovery of analysis of the sample procedure was assessed and proved adequate for the test. At a nominal concentration of 0.2 mg/L, a mean percentage recovery of 88.6 % was obtained.
Concentrations have not been corrected for recovery of analysis. - Conclusions:
- Interpretation of results: insoluble (< 0.1 mg/L)
The water solubility of tetrabutyltin was determined to be less than or equal to 9.64 x 10^-5 g/L of solution at 20 degrees C. - Executive summary:
The water solubility of tetrabutyltin was determined to be less than or equal to 9.64 x 10^-5 g/L of solution at 20 degrees C, using the flask method, Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.
Reference
Table 1: Summary of Results
Sample | Time shaken at 30 degrees C | Time equilibrated at 20 degrees C | Concentration (g/L) | Solution pH |
1 | 24 | 24 | <9.64 x 10 ^-5 | 5.4 |
2 | 48 | 24 | <9.64 x 10^-5 | 5.5 |
3 | 72 | 24 | <9.64 x 10^-5 | 5.5 |
The linearity of the detector response with respect to concentration was assessed over the nominal concentration range of 0 to 10 mg/L. This was satisfactory with a correlation coefficient of 1.000 being obtained.
Description of key information
The key study, (O'Connor BJ & Mullee DM, 2004) was chosen as the study is conducted to a recognised guideline, has a reliability rating 2 according to the criteria of Klimisch et al. (1997) and is the most recent study.
The water solubility for this study was determined to be less than or equal to 9.64 x 10^-5 g/L of solution at 20 degrees C, using the flask method, Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.
Key value for chemical safety assessment
- Water solubility:
- 0 g/L
- at the temperature of:
- 20 °C
Additional information
The water solubility for the key study was determined to be less than or equal to 9.64 x 10^-5 g/L of solution at 20 degrees C, using the flask method, Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995. The test substance is classed as insoluble.
The following supporting studies are also available for this endpoint:
- The water solubility was estimated to be 6.4E-005 mg/L at 25 deg C according to the SRC.
- Schering AG conducted a test following OECD Guideline No. 105, the column elution method was used for the determination of the water solubility of tetra-n-butyltin. A value of 8.8 mg/L was ascertained. However, the analytical method was not compound specific and hence will include contributions from more water soluble tin impurities etc. Therefore, the actual solubility is likely to be less than the reported value. Therefore a reliablity rating of 3 has been assigned according to the criteria of Klimisch et al. (1997).
- The water solubility was estimated to be 1.889 mg/L at 25 deg C according to EPIWIN estimations.
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