Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 219-283-9 | CAS number: 2402-79-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Phototransformation in air
Administrative data
- Endpoint:
- phototransformation in air
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- supporting study
- Study period:
- 16 January 1991 to 19 February 1992
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Estimate was performed following previously established guidelines and is well documented in a GLP compliant report.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 992
- Report date:
- 1992
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: ECETOC Technical Report No. 3, 1981. An Assessment of Test Methods for Photodegradation of Chemicals in the Environment, p.61
- Deviations:
- no
- GLP compliance:
- yes
Test material
- Reference substance name:
- 2,3,5,6-tetrachloropyridine
- EC Number:
- 219-283-9
- EC Name:
- 2,3,5,6-tetrachloropyridine
- Cas Number:
- 2402-79-1
- Molecular formula:
- C5HCl4N
- IUPAC Name:
- 2,3,5,6-tetrachloropyridine
- Details on test material:
- Lot number WP900914-748 of purity 98.6%
Constituent 1
Study design
- Estimation method (if used):
- An estimate of the photodegradation of the substance was performed following guidelines established in ECETOC Technical Report No. 3, 1981. The UV/visible absorbance spectrum of the substance was measured to determine the potential for direct photolysis. A Perkin-Elmer Lambda 7 UV/VIS Spectrophotometer was used to measure absorbance over wavelengths ranging from 200 to 900 nm.
The method described by Zepp and Cline (1977) was employed to calculate the direct photolysis of the substance in both water and air.
A computer model (Atmospheric Oxidation Program, v.1.32 Syracuse Research Corporation, 1981) was employed to evaluate the potential for photooxidation of the substance in the atmosphere. This model assumed attack only by hydroxyl radicals.
Results and discussion
Any other information on results incl. tables
From the calculated rate constants, photolysis half -lives for the substance were determined. The estimated photolysis half-life was a fuinction of both the ф solar and depth of the water column. Photolyis half lives for the substance in water ranged from 18 hours to 101 years (see table below):
Results of direct photolysis in water
Ф Solar
|
Depth of water column (cm) |
Kphotolysis(s-1) |
Half-life |
0.1 |
1 5 50 500 |
1.09 x 10E-5 2.17 x 10E-6 2.17 x 10E-7 2.17 x 10E-8 |
18 hours 3.7 days 37 days 370 days |
0.01 |
1 5 50 500 |
1.09 x 10E-6 2.17 x 10E-7 2.17 x 10E-8 2.17 x 10E-9 |
7.4 days 37 days 370 days 10.1 years |
0.001 |
1 5 50 500 |
1.09 x 10E-7 2.17 x 10E-8 2.17 x 10E-9 2.17 x 10E-10 |
74 days 370 days 10.1 years 101 years |
A computer model was used to estimate the potential for photooxidation of the substance in the atmosphere via attack by hydroxy radicals. The model calculated photooxidation rates based on the molecular structure of the substance and the ability of the substance to react with hydroxyl radicals. Model simulations with the substance resulted in a second-order photooxidation rate constant of 1.52 x 10 -14 cm3 / molecule-sec. Assuming an average atmospheric hydroxyl radical concentration of 5 x 10E5 .OH / cm3, a calculated half-life of 1050 days was determined for photooxidation of the substance in the atmosphere.
Applicant's summary and conclusion
- Conclusions:
- The expected half-life of the substance for direct photlysis in air is approximately one week. The half-life through direct photolysis of the substance in water is approximately 1 year.
Photooxidation of the substance in the atmosphere by attack of hydroxyl radicals results in an estimated half-life of 3 years. - Executive summary:
The expected half-life of the substance for direct photolysis in air is approximately one week. The half-life through direct photolysis of the substance in water is approximately 1 year. These results are derived via a calculation method described by Zepp and Cline.
Photooxidation of the substance in the atmosphere by attack of hydroxyl radicals results in an estimated half-life of 3 years using a computer model (Atmospheric Oxidation Program, v.1.32 Syracuse Research Corporation, 1981).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.