Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Acute toxicity towards plants was tested on Avena sativa (oat), Glycine max (soy bean) and Brassica napus (rape) according to OECD guideline 208. The test was conducted according to OECD 208 using Chlorhexidine digluconate as test substance. As Chlorhexidine base is the active component, the results can be converted to equivalents of CHD-Base. No effects on seedling emergence were observed at the highest concentrations tested (NOECs were always ≥563 mg CHD-Base/kg dry soil). Seedling growth, as determined by shoot fresh-weight and -height, was a more sensitive endpoint displaying EC50s between 296 and >563 mg CHD-Base/kg dry soil.

In a limit test according to OECD 207 Chlorhexidine digluconate was found to be not toxic to earthworms at 1000 mg Chlorhexidine digluconate/kg dw, corresponding to 563 mg Chlorhexidine base/kg dw.