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EC number: 272-032-5 | CAS number: 68649-48-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- REPORTING FORMAT FOR THE ANALOGUE APPROACH
see read-across justifocation in section Chapter 13 - Reason / purpose for cross-reference:
- read-across source
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 55
- Sampling time:
- 28 d
- Details on results:
- - The toxicity control attained 45% degradation after 14 days and 55% after 28 days, confirming that the test material was not toxic to the sewage micro-organisms.
- The degradation rate calculated fro the results of DOC analysis was lower than that calculated from oxygen consumption values, which was considered to be due the sampling/analytical variation.
- Validation criteria were all met. - Results with reference substance:
- - Aniline, the reference substance, attained 76% degradation after 14 days and 89% after 28 days, confirming the suitability of the test inoculum and test conditions.
- 85% degradation was calculated, after 28 days, using the DOC analysis from Days 0 and 28. - Validity criteria fulfilled:
- yes
- Interpretation of results:
- other: Not readily biodegradable.
- Conclusions:
- Under the conditions of the test, the test material attained 55% degradation after 28 days, according to OECD 301F the test material is considered to be not readily biodegradable.
- Executive summary:
In a GLP compliant study performed to the standardised guideline OECD 301F the ready biodegradability of the test material was determined by culturing predominantly domestic sewage sludge micro-organisms with the test material for 28 days. The biodegradability of the test material was determined by measuring oxygen consumption daily. Under the conditions of the test, the test material attained 55% degradation after 28 days, according to OECD 301F the test material is considered to be not readily biodegradable.
Reference
Table 1. BOD and Biodegradation Values
Sample | ThOD (mg O2/l) | Day 7 | Day 14 | Day 28 | ||||
BOD (mg O2/l) | Degradation (%) | BOD (mg O2/l) | Degradation (%) | BOD (mg O2/l) | Degradation (%) | Mean degradation (%) | ||
Control R1 | - | 10.88 | - | 18.40 | - | 29.48 | - | - |
Control R2 | - | 10.38 | - | 18.66 | - | 31.18 | - | |
Aniline | 309 | 19.50 | 3 | 252.10 | 76 | 306.02 | 89 | - |
Test Material R1 | 265 | 87.96 | 29 | 139.66 | 46 | 174.98 | 55 | 55.00 |
Test Material R2 | 265 | 92.12 | 31 | 132.90 | 43 | 177.38 | 55 | |
Toxicity Control | 574 | 234.86 | 3 | 275.76 | 45 | 347.96 | 55 | - |
Table 2. DOC and Degradation Values
Sample | Theoretical Carbon Content (mg C/l) | Day 0 | Day 28 | ||||
DOC (mg C/l) | DOC (mg C/l) | ||||||
Measured | Corrected for Control Value | % Theoretical Carbon Content | Measured | Corrected for Mean Control Values | Degradation (%) | ||
Control R1 | - | 3.48 | - | - | 1.71 | - | - |
Control R2 | - | - | - | - | 1.54 | - | - |
Aniline | 77.38 | 79.39 | 75.91 | 98.00 | 12.64 | 11.01 | 85 |
RO Water | - | 1.99 | - | - | - | - | - |
Aniline Stock Solution | 77.38 | 79.38 | 77.39 | 100.00 | - | - | - |
Description of key information
The ready biodegradability of the test substance was determined in a key study (Clarke, 2003) to be not readily biodegradable.
The study was performed according to GLP and the standardised guidelines OECD 301F and EPA OPPTS 835.3110.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
The key study (Clarke, 2003) is a GLP compliant study which was performed in line with standardised guidelines with a sufficient level of detail to assess the quality of the study. Predominantly domestic sewage sludge micro-organisms were exposed to the test material at 100 mg/l for 28 days under aerobic conditions. Oxygen consumption was recorded daily to quantify the observed degradation. Under the conditions of the test 55% degradation was seen, which is classed as not being readily biodegradable. The study was performed to a good standard and was assigned a reliability score of 1 using the principles for assessing data quality as set out in Klimisch (1997).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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