Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: other routes

Currently viewing:

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: application method is not relevant for the human situation

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1986

Materials and methods

Principles of method if other than guideline:
other: no further data
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
m-cresol
EC Number:
203-577-9
EC Name:
m-cresol
Cas Number:
108-39-4
Molecular formula:
C7H8O
IUPAC Name:
3-Methylphenol
Details on test material:
no data on purity

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
other: migrated dataset
Doses:
200-3200 mg/kg bw as 10 % solution in 2 % NaCS
No. of animals per sex per dose:
10
Control animals:
other: migrated dataset

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
400 mg/kg bw

Any other information on results incl. tables

RS-Freetext:
Signs of intoxication:
labored respiration, cyanosis, dark eyes, prostration
time of death: 8 hrs to 1 day

Applicant's summary and conclusion

Executive summary:

migrated dataset