Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 235-469-2 | CAS number: 12237-63-7 This substance is identified in the Colour Index by Colour Index Constitution Number, C.I. 45160:2.
Endpoint summary
Administrative data
Description of key information
Hydrolysis:
On the basis of the experimental studies of the structurally and functionally similar read across chemical and applying the weight of evidence approach, the hydrolysis half-life value of the test chemical can be expected to be 48 yrs and 5 yrs at pH 7 and 8, respectively with a second order hydrolysis rate constant of 0.0046 L/mol-sec, respectively or > 20 days at pH range 7.4 to 7.8 and a temperature of 20.1 to 20.5⁰C, respectively. Thus, based on this half-life value, it can be concluded that the test chemical is hydrolytically stable.
Additional information
Hydrolysis:
Data available for the structurally and functionally similar read across chemicals has been reviewed to determine the half-life of the test chemical . The studies are as mentioned below:
The half-life and base catalyzed second order hydrolysis rate constant was determined using a structure estimation method of the test chemical. The second order hydrolysis rate constant of test chemical was determined to be 0.0046L/mol-sec with a corresponding half-lives of 48 yrs and 5 yrs at pH 7 and 8, respectively. Based on the half-life value, it is concluded that the test chemical was considered to be hydrolytically stable.
The half-life of the test chemical was determined at different pH range. The study was performedat apH range7.4 to 7.8 and a temperature of 20.1 to 20.5⁰C, respectively.The test substance was dissolved in dechlorinated tap water. The concentration of the test substance was measured in the supernatant of the test solution centrifuged. The test substance was measured on day 0, 1, 3, 6, 8, 10, 13, 15, 17, and 20 over a 21-day period. The test concentration used was considered to be at saturation in water. Based on the measured concentration of test chemical in water, chemical was reported to be hydrolytically stable at pH range7.4 to 7.8 and a temperature of 20.1 to 20.5 ⁰C for 20 days. Test chemical appears to be in equilibrium and does not appear to be breaking down in water. The concentration of test chemical is not decreasing with time. Thus, the half-life value of test chemical was determined to be > 20 days and on the basis of this, test chemical was considered to be stable in water.
On the basis of the experimental studies of the structurally and functionally similar read across chemical and applying the weight of evidence approach, the hydrolysis half-life value of the test chemical can be expected to be 48 yrs and 5 yrs at pH 7 and 8, respectively with a second order hydrolysis rate constant of 0.0046 L/mol-sec, respectively or > 20 days at pH range 7.4 to 7.8 and a temperature of 20.1 to 20.5⁰C, respectively. Thus, based on this half-life value, it can be concluded that the test chemical is hydrolytically stable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
