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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)

Data source

Reference
Reference Type:
review article or handbook
Title:
RTECS doc no : CV5050000
Author:
RTECS database
Year:
2012
Bibliographic source:
RTECS (Registry of Toxic Effects of Chemical Substances); NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,100,1982

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other:
Principles of method if other than guideline:
Data is from RTECS
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
Exalamide
EC Number:
258-504-3
EC Name:
Exalamide
Cas Number:
53370-90-4
IUPAC Name:
2-(hexyloxy)benzamide
Details on test material:
- Name of test material : exalamide

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
> 5 000 mg/kg bw
Based on:
test mat.
Remarks on result:
other: Other details not available
Clinical signs:
other: Details of toxic effects not reported other than lethal dose value.

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
Oral acute toxicity (LD50) value for exalamide in rat is greater that 5000 mg/kg.
Executive summary:

Oral acute toxicity (LD50) value for exalamide in rat is greater that 5000 mg/kg. This value shows that exalamide is not toxic by oral route.