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EC number: 208-857-4 | CAS number: 544-01-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Semi-static GLP compliant acute toxicity test with Oryzias latipes (medaka) exposed to diisopentyl ether, conducted in accordance with OECD 203
and supporting chemical analysis.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 6.82 mg/L
Additional information
A GLP compliant 96 hour semi-static acute toxicity test with Oryzias latipes (medaka) was performed in accordance with OECD 203 to assess the toxicity of diisopentyl ether. Nominal test concentrations were: 1,0, 1.8, 3.2, 5.6 and 10 mg/L (spacing factor 1.8), a diluent control was also included and measured concentrations were determined. The results are based on geometric mean measured concentrations. At the end of the test the 96 hour LC50 was calculated to be 6.82 mg/L (CI 95% 4.76 to 9.78 mg/L). The NOEC based on mortality was 4.76 mg/L.
A 48 hour LC50 value of 4.7 mg/L has been reported in a bioaccumulation study (NITE, 1983), however no details on test method are given and the test duration is shorter than the recommended 96 hour according to OECD Guideline 203.
The experimental measurement according to GLP and OECD guidelines was considered as the key study, compared to the value reported as part of a bioaccumulation study.
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