Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 608-544-6 | CAS number: 3082-64-2
Endpoint summary
Administrative data
Description of key information
oral
rat (OECD 407) NOEL (m/f): >15 mg/kg bw/day (highest dose tested) [SafePharm Laboratories, 2004]
dermal
Actually, there is no information available.
inhalation
Actually, there is no information available.
Key value for chemical safety assessment
Repeated dose toxicity: via oral route - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- NOAEL
- 15 mg/kg bw/day
Additional information
oral
Currently, there are no studies available. Nevertheless, there is a reliable study existing, which may serve as read across: (S)-1-Phenyl-propylamine (CAS 3789-59-1).
A 28-day subacute study was conducted with rats which received 1.5, 5 or 15 mg/kg/d (S)-1-phenyl-propylamine (CAS 3789-59-1, read across) by gavage. Based on the results, the NOEL of the test substance was defined at the highest dose level tested. [SafePharm Laboratories, 2004]
dermal
Currently, there is no information available.
inhalation
Currently, there is no information available.
Justification for classification or non-classification
Based on the available data for (S)-1 -Phenyl-propylamine (CAS 3789-59-1, read across), (R)-1-Phenyl-propylamine is not subject to C&L according to Regulation 1272/2008/EC and Directive 67/548/EEC.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
