Registration Dossier
Registration Dossier
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EC number: 230-022-8 | CAS number: 6915-15-7
Partition coefficient
Administrative data
Link to relevant study record(s)
Description of key information
Distribution coefficients (Log D) at 20 deg C:
log D = - 1.16 at pH= 2.0 (stomach)
log D = - 3.53 at pH= 5.5 (skin)
log D = - 6.09 at pH= 7.4 (plasma)
log D = - 6.14 at pH= 8.0 (river)
Key value for chemical safety assessment
- Log Kow (Log Pow):
- -6.14
- at the temperature of:
- 20 °C
Additional information
Databases of experimental values report a log10 Pow of malic acid as being - 1.26, typical of the undissociated form.
In case of human and environmental assessment, because we need to consider all the charge-state forms of malic acid dissolved in water and in octanol, the log D (distribution coefficients) were estimated taking account for the pH dependence of the substance in aqueous solution.
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