α-acetyl-γ-butyrolactone

Guidance on Safe Use

First-aid measures

Description of first aid measures:

-General advice:

Move out of dangerous area.

Place and transport victim in stable position (lying sideways).

Remove contaminated clothing immediately and dispose of safely.

- Inhalation:

Move to fresh air.

Keep patient warm and at rest.

Call a physician or poison control center immediately.

- Skin contact:

Wash off thoroughly with plenty of soap and water, if available with polyethyleneglycol 400, subsequently rinse with water.

- Eye contact:

Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes.

Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye.

Get medical attention if irritation develops and persists.

- Ingestion:

Rinse mouth. Do NOT induce vomiting.

Call a physician or poison control center immediately.

Most important symptoms and effects, both acute and delayed

Symptoms

The following symptoms may occur:, Skin disorders, Itching, Irritation, Redness, Blistering

Indication of any immediate medical attention and special treatment needed:

- Treatment:

Treat symptomatically.

In case of ingestion gastric lavage should be considered in cases of significant ingestions only within the first 2 hours. However, the application of aactivated charcoal and sodium sulphate is always advisable.

There is no specific antidote.

Fire-fighting measures

FIREFIGHTING MEASURES

Extinguishing media

Suitable: Water spray, Dry chemical, Foam

Unsuitable: High volume water jet

Special hazards arising from the substance or mixture: Hazardous decomposition products due to incomplete combustion

Advice for firefighters

Special protective equipment for firefighters: Wear self-contained breathing apparatus and protective suit.

Further information: Keep out of smoke. Fight fire from upwind position. Evacuate personnel to safe areas. Do not allow run-off from fire fighting to enter drains or water courses.

Accidental release measures

Personal precautions, protective equipment and emergency procedures

Precautions: Keep unauthorized people away. Isolate hazard area. Avoid contact with spilled product or contaminated surfaces. Remove all sources of ignition.

Environmental precautions: Do not contaminate surface or ground water by cleaning equipment or disposal of wastes, including equipment wash water. Do not allow to get into surface water, drains and ground water.

Methods and materials for containment and cleaning up

Methods for cleaning up: Dike area to prevent runoff. Collect and transfer the product into a properly labelled and tightly closed container. Clean contaminated floors and objects thoroughly, observing environmental regulations. Decontaminate tools and equipment following cleanup. Soak up with inert absorbent material (e.g. sand, silica gel, acid binder, universal binder, sawdust).

Handling and storage

This substance is handled under Strictly Controlled Conditions in accordance with  REACH regulation Article 17(3) for on-site isolated intermediates and, in case the substance is transported to other sites for further processing, the substance should be handled at these sites under the Strictly Controlled Conditions as specified in REACH regulation Article 18(4).  Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at each manufacturing site.

Written confirmation of application of Strictly Controlled Conditions has been received from every affected Distributor and Downstream Processor/User of the Registrant’s intermediate.

Precautions for safe handling

Hygiene measures: Handle in accordance with good industrial hygiene and safety practice. Wash hands thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco, using the toilet or applying cosmetics.

Conditions for safe storage, including any incompatibilities

Requirements for storage areas and containers: Keep containers tightly closed in a dry, cool and well-ventilated place.

Transport information

Land transport (UN RTDG/ADR/RID)

UN number:

not classified

Shipping

SpecialProvisions

Inland waterway transport (UN RTDG/ADN(R))

UN number:

not classified

Shipping

Remarks

Marine transport (UN RTDG/IMDG)

UN number:

not classified

Shipping

Remarks

Air transport (UN RTDG/ICAO/IATA)

UN number:

not classified

Shipping

Remarks

SpecialProvisions

Exposure controls / personal protection

This substance is handled under Strictly Controlled Conditions in accordance with  REACH regulation Article 17(3) for on-site isolated intermediates and, in case the substance is transported to other sites for further processing, the substance should be handled at these sites under the Strictly Controlled Conditions as specified in REACH regulation Article 18(4).  Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at each manufacturing site.

Written confirmation of application of Strictly Controlled Conditions has been received from every affected Distributor and Downstream Processor/User of the Registrant’s intermediate.

Control parameters

Components                     CAS-No.       Control parameters       Update       Basis

alphaα-Acetyl-gamma-butyrolactone       517-23-7       50 ppm (TWA)              OES BCS*

*OES BCS: Internal Bayer AG, Crop Science Division "Occupational Exposure Standard"

Exposure controls

Respiratory protection: In case of insufficient ventilation wear suitable respiratory equipment.

Hand protection: Nitrile rubber gloves

Eye protection: Tightly fitting safety goggles

Skin and body protection: Use suitable protective clothing, gloves and footwear, selected with regard to use conditions and exposure potential.

General protective measures: Avoid contact with skin and eyes.

Use only in area provided with appropriate exhaust ventilation.

Stability and reactivity

Reactivity: Not applicable

Conditions to avoid: Heat, flames and sparks.

Incompatible materials: Bases, Strong oxidizing agents, Strong acids

Hazardous decomposition products: Carbon monoxide, Carbon dioxide (CO2)

Disposal considerations

This substance is handled under Strictly Controlled Conditions in accordance with  REACH regulation Article 17(3) for on-site isolated intermediates and, in case the substance is transported to other sites for further processing, the substance should be handled at these sites under the Strictly Controlled Conditions as specified in REACH regulation Article 18(4).  Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at each manufacturing site.

Written confirmation of application of Strictly Controlled Conditions has been received from every affected Distributor and Downstream Processor/User of the Registrant’s intermediate.

During the whole life cycle of the substance all necessary measures in accordance to art. 18(4) of (EC) 1907/2006 are undertaken. The substance is handled under strictly controlled conditions.  

Waste treatment methods

Product

In accordance with current regulations and, if necessary, after consultation with the site operator and/or with the responsible authority, the product may be taken to a waste disposal site or incineration plant.

Contaminated packaging: Triple rinse containers. Do not re-use empty containers. Consult state and local regulations regarding the proper disposal of container.