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Diss Factsheets
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EC number: 291-367-8 | CAS number: 90387-90-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Graphite, acid-treated is an inorganic solid, consisting of natural graphite and variable amounts of either intercalated nitric acid or acetic acid. The main component – graphite – is a naturally occurring inorganic solid substance which is insoluble in water. Due to its physico-chemical properties, i.e. absence of lipophilic functional groups which would enhance the lipid (fat) solubilisation properties and therefore facilitate the uptake into the organism, graphite itself can be regarded as not bioaccumulative and harmless. Graphite cannot degrade and does not adsorb to organic matter in soil or sediment (see IUCLID points 5.2 and 5.4.1).
The nitrite and the nitrate are the corresponding reduction/oxidation counterparts in which they form intermediates in the course of the nitrogen cycle. In the environment, bacteria of the genus Nitrobacter oxidise nitrites to nitrates. Nitrates are reduced to nitrogen by anaerobic bacteria present in soil and sediment (OECD SIDS Report for sodium nitrite; 2005). Acetic acid is a metabolisation and degradation product and occurs in various plants, such as juniper or tobacco.
The low hazardous potential to microorganisms can be concluded from the negative testing results of a pre-incubation test (Ames Test) performed with several Salmonella typhimurium strains in order to investigate the potential of extracts of graphite, acid-treated to induce gene mutations. No cytotoxic effects of the test item extracts were noted in any of the five tester strains used (with and without metabolic activation) (see section 7.6.1 of the IUCLID dossier).
Production, handling and use of graphite, acid-treated only take place at a small number of industrial sites without releases of this substance to the environment or to waste water streams under reasonably foreseeable conditions of use. Therefore, performance of a study on toxicity to activated sludge is not required under Regulation (EC) No 1907/2006 (REACH).
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.