Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 200-353-2 | CAS number: 57-88-5
Endpoint summary
Administrative data
Description of key information
Additional information
In accordance with column 2 of REACH Annex VIII, the hydrolysis study as a function of pH does not need to be conducted as the substance is highly insoluble in water (30.6 µg/L).
Cholesterol was found to be inherently biodegradable according to the OECD 302C (Modified MITI (II) test): 74% degradation in 28 days.
Although no measured BCF value is available, it is anticipated that the bioaccumulation potential of cholesterol in organisms is low based on the cholesterol homeostasis and supporting QSARs.
Three log Koc values were estimated according to different calculation models. All models indicated a high adsorption potential of cholesterol (logKoc between 4.94 and 6.58). A logKoc of 4.94 was chosen as worst case approach value.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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