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Diss Factsheets
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EC number: 618-460-1 | CAS number: 9010-89-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Additional information
Two acute toxicity studies are available for the test substance Hexanedioic acid, polymer with 2,2'-oxybis[ethanol]: an oral study according to OECD Guideline 423 and a dermal study according to OECD Guideline 402.
In the acute oral toxicity study, 2000 mg/kg of the undiluted test item Polyesterol 90212 were administered by gavage to two test groups of three fasted Wistar rats each (females). Mortality did not occur in any of the test groups, and no pathological findings were recorded. Clinical signs occuring within the first 2 hours after administration were observed in the first test group only and included impaired general state and piloerection. The second test group was free of clinical signs. Stagnation of body weights was observed in both groups in the second week. The acute oral LD50 was calculated to be > 2000 mg/kg bw.
In an acute dermal toxicity study, young adult Wistar rats (5 males and 5 females) were exposed to a single dose of 2000 mg/kg bw of Polyesterol 90212 (undiluted) to the clipped skin and covered by semi-occlusive dressing for 24 hours. The animals were observed for 14 days. No signs of systemic toxicity or mortality were observed in the animals.
The only test item-related local effect was very slight (grade 1) erythema in two animals, occuring within the first two days after administration. The acute dermal LD50 was determined to be > 2000 mg/kg bw.
Justification for classification or non-classification
Based on the available information, classification according to Regulation (EC) 1272/2008 and Directive 65/548/EEC is not warranted.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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