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Diss Factsheets
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EC number: 229-662-0 | CAS number: 6642-31-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2002-06-12 (experimental phase)
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Version / remarks:
- adopted July 27, 1995
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Version / remarks:
- EEC Directive 92/69, Part A, Methods for the determination of physico-chemical properties, A.1 "Melting/Freezing temperature", EEC Publication No. L383, December 1992.
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- thermal analysis
- Remarks:
- via Differential Scanning Calorimeter
- Specific details on test material used for the study:
- - Storage condition of test material: at room temperature (at about 20 °C)
- Key result
- Melting / freezing pt.:
- 299 °C
- Atm. press.:
- 1 013 hPa
- Decomposition:
- no
- Remarks on result:
- other:
- Remarks:
- Mean of two runs. During these runs, the samples lost 24.3 % and 37.3 % of their mass, respectively. After the measurement both samples were colored brownish yellow and of a clear melt.
- Conclusions:
- The melting point of 1,3-DIMETHYL-4-AMINOURACIL is 299.0 °C±0.5°C.
- Executive summary:
The determination of the melting point / melting range of the test item was performed according to the EEC Directive 92/69, A.1 "Melting/Freezing temperature", December 1992 and to the OECD Guideline No. 102;" Melting point / melting range", adopted July 27, 1995, under GLP. Thermal analysis was performed using a DSC apparatus.
The DSC-curve of the preliminary test (heating rate of 20 K/min from 25 °C to 400 °C) shows that an endothermic heat effect, the melting, was observed at 304.7 °C. After the experiment, the sample had lost about 62 % of its mass and the color of the sample was brownish black and carbonized.
In order to determine the melting more precisely, further DSC-runs were recorded between 275 °C and 325 °C with a heating rate of 5 K/min. In the first main test run, the melting of 1,3-DIMETHYL-4-AMINOURACIL was determined at 299.4 °C. The melting of the test item during the second main test run was determined to be at 298.7 °C. During these runs, the samples lost 24.3 % and 37.3 % of their mass, respectively.
In conclusion, the melting point of 1,3-DIMETHYL-4-AMINOURACIL was determined to be 299.0 °C±0.5°C.
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP-guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- thermal analysis
- Key result
- Melting / freezing pt.:
- 296 °C
- Atm. press.:
- 1 013 hPa
- Decomposition:
- no
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: peer reviewed database
- Guideline:
- other: no data
- GLP compliance:
- no
- Key result
- Melting / freezing pt.:
- 295 °C
Referenceopen allclose all
The melting point of 1,3-DIMETHYL-4-AMINOURACIL was determined to be 299.0 °C±0.5°C which is equal to 572.2 K ± 0.5 K.
Description of key information
Melting Point:
296°C at 1013 hPa (thermal analysis, OECD 102, GLP)
295°C (database entry)
299°C at 1013 hPa (thermal analysis, OECD 102, GLP)
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- 299 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.