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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Administrative data

Endpoint:
bioaccumulation in aquatic species, other
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Prediction model
Title:
Bioaccumulation by Environmental Science Center’s PBT profiler
Author:
Environmental Science Center
Year:
2010
Bibliographic source:
PBT profiler, Office of Chemical Safety and Pollution Prevention , U.S. Environmental Protection Agency; version 1.301

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: Modeling database
Principles of method if other than guideline:
PBT profiler database
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
3-amino-4-hydroxybenzenesulphonic acid
EC Number:
202-662-8
EC Name:
3-amino-4-hydroxybenzenesulphonic acid
Cas Number:
98-37-3
Molecular formula:
C6H7NO4S
IUPAC Name:
3-amino-4-hydroxybenzenesulphonic acid
Test material form:
solid: crystalline
Details on test material:
- Name of test material : 3-amino-4-hydroxybenzenesulphonic acid
-Substance type-organic
-physical state-crystalline solid.
Radiolabelling:
not specified

Test solutions

Vehicle:
not specified

Test organisms

Test organisms (species):
other: Fish

Study design

Route of exposure:
aqueous
Test type:
other: estimated values
Water / sediment media type:
not specified

Test conditions

Salinity:
Not reported

Results and discussion

Bioaccumulation factor
Type:
BCF
Value:
3.2
Basis:
not specified
Calculation basis:
other: estimated
Remarks on result:
other: other details not available

Applicant's summary and conclusion

Conclusions:
Bioconcentration factor (BCF) value of 3-amino-4-hydroxybenzenesulphonic acid is estimated to be 3.2 . This value suggests that 3-amino-4-hydroxybenzenesulphonic acid is not expected to bioaccumulate in the food chain.
Executive summary:

Bioaccumulation is the process by which the chemical concentration in an aquatic organism achieves a level that exceeds that in water as a result of chemical uptake through all possible routes of exposure. The relationship between Bioaccumulation and Bioconcentration is that,chemicals that have potential to bioconcentrate also have potential to bioaccumulate.Bioaccumulation is closely related to bioconcentration factor (BCF)

 

The BCF value of 3-amino-4-hydroxybenzenesulphonic acid is estimated to be 3.2 This value indicates that 3-amino-4-hydroxybenzenesulphonic acide is not expected to bioaccumulate in the food chain because it does not exceed the EPA bioconcentration criteria of >=1000.