Registration Dossier
Registration Dossier
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EC number: 215-158-8 | CAS number: 1308-14-1
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 1991
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Data from IUCLID dataset, original study not available.
Data source
Reference
- Reference Type:
- secondary source
- Title:
- IUCLID Dataset for: dichromium trioxide hydrate
- Author:
- European Commision
- Year:
- 2 000
- Bibliographic source:
- http://esis.jrc.ec.europa.eu/doc/IUCLID/data_sheets/1308141.pdf
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 401 (Acute Oral Toxicity)
- Deviations:
- not specified
- GLP compliance:
- yes
Test material
- Reference substance name:
- Chromium (III) hydroxide
- EC Number:
- 215-158-8
- EC Name:
- Chromium (III) hydroxide
- Cas Number:
- 1308-14-1
- Molecular formula:
- CrH3O3
- IUPAC Name:
- chromium (III) hydroxide
- Reference substance name:
- Chromium hydroxide
- EC Number:
- 235-725-3
- EC Name:
- Chromium hydroxide
- Cas Number:
- 12626-43-6
- IUPAC Name:
- chromium(2+) dihydroxide
- Reference substance name:
- Chromium(III) hydroxide
- IUPAC Name:
- Chromium(III) hydroxide
- Reference substance name:
- Chromium(III) hydroxide
- IUPAC Name:
- Chromium(III) hydroxide
- Test material form:
- not specified
Constituent 1
Constituent 2
Constituent 3
Constituent 4
Test animals
- Species:
- rat
Administration / exposure
- Route of administration:
- oral: unspecified
- Doses:
- 5000 mg/kg bw
Results and discussion
Effect levels
- Dose descriptor:
- LD50
- Effect level:
- > 5 000 mg/kg bw
Applicant's summary and conclusion
- Conclusions:
- The acute oral toxicity is > 5000 mg/kg bw.
- Executive summary:
In an acute oral toxicity study (according to OECD 401 test guideline) rats were feed a single oral dose of chromium(III) hydroxide (unspecified) at a dose of 5000 mg/kg bw.Oral LD50was determined to be >5000 mg/kg.
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