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A mixture of: 4-(2,2,3-trimethylcyclopent-3-en-1-yl)-1-methyl-2-oxabicyclo[2.2.2]octane; 1-(2,2,3-trimethylcyclopent-3-en-1-yl)-5-methyl-6-oxabicyclo[3.2.1]octane; spiro[cyclohex-3-en-1-yl-[(4,5,6,6a-tetrahydro-3,6',6',6'a-tetramethyl)-1,3'(3'aH)-[2H]cyclopenta[b]furan]; spiro[cyclohex-3-en-1-yl-[4,5,6,6a-tetrahydro-4,6',6',6'a-tetramethyl)-1,3'(3'aH)-[2H]cyclopenta[b]]furan]
EC number: 422-040-1 | CAS number: 426218-78-2 CASSIFFIX
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
The substance has a half-life of 22 days at pH 7 and 25 °C.
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 22 d
- at the temperature of:
- 25 °C
Additional information
Hydrolysis of the substance as a function of pH was examined in a study according to OECD TG 111 and in compliance with GLP (Huntingdon, 1995). Test solutions were prepared in stoppered glass flasks (shielded from light) by adding defined nominal concentrations to sterile buffer solutions with pH4, 7, and 9. Sample solutions were taken at various times, the concentration of each sample solution determined by GC, and hydrolysis rates and half-lives determined.
In the preliminary test significant hydrolysis of the test substance was observed at pH 4 (79.8%), pH 7 (79.5% ) and pH 9 (71.9%) after 5 days at 50°C. Therefore higher tier testing were performed. In a first test (Test 1) reaction orders were determined by determining plots of log10 (percent remaining) versus time for Test 1 (50°C). At pH 7 the data points did not fall on a straight line indicating that the hydrolysis reaction was not a pseudo-first order reaction. At pH 4 and 9 the data points were inconclusive. Therefore, for pH 4, 7 and 9, an additional test (Test 2) was performed. In this second test estimates of the half-lives at pH 4, 7 and 9 at 25°C were obtained graphically from plots of log10 (percentage remaining) versus time for Test 2. As the plots were non-linear, the times taken for the test substance concentration to drop to 50% (log10 (percentage remaining) = 1.70) were read directly from the graphs. Based on this approach, the hydrolysis reaction of the test substance at 25°C and pH 4, 7 and 9 occurred with an estimated half-life time of 710 hours (ca. 30 days), 520 hours (ca. 22 days) and 830 hours (ca. 30 days), respectively.
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