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Diss Factsheets
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EC number: 201-873-2 | CAS number: 88-99-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Bioaccumulation: terrestrial
Administrative data
Link to relevant study record(s)
- Endpoint:
- bioaccumulation: terrestrial
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Principles of method if other than guideline:
- Greenhouse study with 14C-phthalic acid
- GLP compliance:
- no
- Radiolabelling:
- yes
- Vehicle:
- yes
- Details on preparation and application of test substrate:
- 14C-labelled phthalic acid added to unlabelled phthalic acid,
and dissolved in ethanol - Test organisms (species):
- other: plants
- Type:
- BCF
- Value:
- 0.013
- Basis:
- other: plant tissue
- Calculation basis:
- steady state
- Type:
- BCF
- Value:
- 0.005
- Basis:
- other: seeds
- Calculation basis:
- steady state
- Executive summary:
In green house studies 14C-phthalic acid was applied to soil planted with wheat (Triticum aestivum)/corn (Zea mays) or soybeans (Glycine max)/tall fescue (Festuca arundinacea). For phthalic acid the bioaccumulation ratios were 0.013 for plants and 0.0046 for seeds. TLC analysis showed that the percent of the extractable 14C still in phthalic acid, was 5 % in corn and fescue, 15 % in soybean, 9 % in wheat plants, and the highest for wheat seed (47 %) (Dorney et al., 1985).
Reference
Bioaccumulation factor (BF) [ppm in plant tissue/ppm initial soil application (dry weight basis)] averaged for all tested plants and seeds:
plant : 0.013
seed : 0.0046
Extractable 14C phthalic acid (%) after final harvest:
corn : 4.5
fescue : 5.2
mature wheat : 9.2
wheat seed : 46.7
mature soybean plants: 15.3
Average bioaccumulation ratios for total 14C:
- for seeds : 0.0005
- for plants : 0.003
Description of key information
In green house studies using 14C-phthalic acid as test substance bioaccumulation ratios of 0.013 for plants and 0.0046 for seeds were obtained (Dorney et al., 1985). This study demonstrates the relatively low potential for bioaccumulation of phthalic acid in plants.
Key value for chemical safety assessment
- BCF (terrestrial species):
- 0.013 dimensionless
Additional information
In green house studies 14C-phthalic acid was applied to soil planted with wheat (Triticum aestivum) /corn (Zea mays) or soybeans (Glycine max) /tall fescue (Festuca arundinacea). For phthalic acid the bioaccumulation ratios were 0.013 for plants and 0.0046 for seeds. TLC analysis showed that the percent of the extractable 14C still in phthalic acid, was 5 % in corn and fescue, 15 % in soybean, 9 % in wheat plants, and the highest for wheat seed (47 %) (Dorney et al., 1985). This study demonstrates the relatively low potential for accumulation of phthalic acid in plants.
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