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EC number: 619-079-3 | CAS number: 949109-75-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Biodegradation in water: screening tests: 90-92% in 28 days (BODIS). Readily biodegradable.
Key value for chemical safety assessment
Additional information
90-92% biodegradation was attained in 28 days in a reliable BODIS study. The 10-day window is not relevant for substances such as this that are a mixture of homologous compounds (ECHA, 2008). The substance is readily biodegradable.
A BODIS test (Biological Oxygen Demand of Insoluble Chemicals), or two-phase closed bottle test, is a method developed to investigate the ultimate aerobic degradability of poorly soluble chemicals (SCHER, 2005). BOD bottles and an oxygen electrode are used as in the OECD 301D Closed Bottle Test. One third of the bottle (headspace) acts as an oxygen reservoir. Consequently, higher test substance concentrations than in the OECD 301D test can be used, as the oxygen concentration in the (saturated) medium is no longer the limiting factor for degradation. Concentrations of up to 100 mg COD/l can be weighed directly into the test flasks.
A comparison of the biodegradation results obtained with the ISO 10708 to those acquired by other ready biodegradation methods has been carried out (SCHER, 2005). It was concluded that using the biodegradability pass criterion of the 60% BOD/COD the biodegradation results obtained with the BODIS test are consistent (i.e. results in a similar final evaluation) with those obtained with the OECD ready biodegradability methods.
The phytosterol used in the study was refined phytosterol extracted from soybean oil. The concentration of test substance was 100 mg COD/l.
In two independent series of tests reliably high biochemical oxygen consumption rates were determined of 90 and 92% BOD/COD (the theoretical COD determined for the substance was2.94mgO2/mg test substance).
SCHER (2005) EUROPEAN COMMISSION. SCIENTIFIC COMMITTEE ON HEALTH AND ENVIRONMENTAL RISKS (SCHER) Opinion on “Compatibility of the ISO standard 10708 (biodegradability test method) with the ultimate biodegradability requirements imposed through Annex III of Regulation 648/2004 of Parliament and of the Council” Adopted by the SCHER during the 3rd plenary of 28 January 2005.
For completeness, a range of supporting studies from the open literature has been reviewed (see Appendix I of the CSR). It can be concluded from these studies that plant sterols degrade rapidly, although their fate in WWTP should (in the normal way for exposure assessment) take operational conditions into account.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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