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Diss Factsheets
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EC number: 457-850-4 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Guidance on Safe Use
Administrative data
First-aid measures
Emergency measure - Inhalation: Remove the person from exposed area to fresh area
immediately. Get medical advice following prolonged exposure
.
Emergency measure - Eyes: Wash immediately with large amounts of water or normal
saline; keep the eyelid open with the finger. Get medical
advise if symptoms appear.
Emergency measure - Skin: Remove contaminated clothes and shoes immediately. Wash
affected area with soap or mild detergent and large amount
of water until no evidence of chemical remains (15-20
minutes). Get medical attention if symptoms appear.
Emergency measure - Ingestion: If swallowed wash out mouth with water provided person is
conscious. Do not induce vomiting. Treat symptomatically and
supportively. Get medical advice if symptoms appear.
Fire-fighting measures
Recommended extinguishing agent: Dry chemical, carbon dioxide, water spray or regular foam
Product arising from burning: Thermal decomposition or combustion may include toxic and
hazardous fumes.
Product determined by test: N
Protective equipment: Safety Shoes/Boots for Schwarz Pharma Employees:
All safety Shoes/Boots used on site must as a minimum have
antistatic properties, conform to EN 345 S1 and be CE
Marked. Personnel working in production, warehouse and
maintenance areas must wear safety boots. This is to provide
the wearer with extra ankle support. Personnel in other
areas have a choice between safety shoes and safety boots.
Safety Shoes/Boots for Contractors:
All safety Shoes/Boots used on site must as a minimum have
antistatic properties, conform to EN 345 S3 and be CE
Marked. Contractors working at Schwarz Pharma Limited must
provide their own safety boots.
Safety Shoes/Boots for Visitors:
All safety Shoes/Boots used on site must as a minimum have
antistatic properties, conform to EN 345 S1 and be CE
Marked. Visitors on site will be provided with Safety shoes
at reception and should be returned to reception after use.
These shoes are then sanitised with a shoe sanitiser before
being returned to storage.
Safety Wellingtons:
All Safety Wellingtons used on site must as a minimum, have
antistatic properties, conform to EN 345 S1 and be CE
marked.
Hearing Protection:
Two forms of hearing protection are available to Schwarz
Pharma personnel working on site. Helmet mounted ear muffs
or Ear plugs. Both of which must conform to EN 352. Hearing
protection must provide sufficient attenuation to bring
Noise exposure to below 80 dB(A).
Safety helmets:
Helmets must be worn by all personnel beyond the red line
area including contractors and visitors. All helmets must be
CE marked and must conform to EN397 1995. All Schwarz
Pharma Limited employees will have their Helmets changed
every two years or sooner if they have been damaged.
Hi Viz Traffic Jackets or Hi Viz Vests:
Must be worn by all contractors on site. Schwarx Pharma
personnel not involved with routine chemical handling will
also be provided with Hi Viz Traffic Jackets or Hi Viz
Vests. All Hi Viz clothing must be CE marked and conform to
EN 471.
Gas masks:
All full face gas masks must be CE marked and conform to EN
136.
Safety glasses:
General safety glasses must be CE marked and conform to EN
166. These glasses should be at lease impact resistant to
level 1F of the standard. Safety Over glasses must be CE
marked and conform to EN 166. These glasses should be at
lease impact resistant to level 1F of the standard.
Disposable white overalls:
Such overalls must be CE marked and should be Antistatic to
conform to EN1149. These suits should have limited Splash
protection against chemicals to a minimum Type 6.
Breathing Air Hoses:
Must conform to EN270 or EN 139 Air Hoods must conform to EN
270 and EN 464.
Air Suits must conform to EN 943 part 1. Couplings for same
must conform to EN 270.
Gloves must conform to EN388, EN374 and EN 1149 part -1 and
-2.
Accidental release measures
Emergency measures in case of spillage: Sweep up and place into a suitable container for disposal in
compliance with the national laws.
Dress standard PPE (Personal Protection Equipment) EN
standards for PPE are as follows: EN136 respirator fitted
with and A2B2E2K2-P3 cartridge, gloves used are EN grade 10
gloves, safety glasses rated to EN166 and safety shoes rated
to EN345 S1.
Keep away from sources of ignition.
Handling and storage
Handling: Avoid inhalation, contact and ingestion. When use do not
eat, drink or smoke.
In all working places provide sufficient ventilation.
EN standards for PPE are as follows: EN136 respirator fitted
with an A2B2E2K2-P3 cartridge, gloves used are EN grade 10
gloves, safety glasses rated to EN166 and safety shoes rated
to EN345 S1.
Engeneering controls are as follows:
Local Exhaust Ventilation System in BPC comprises of a
single fan extraction system which discharges into the main
EPA licensed Emission point for the BCP building. The LEV
system is active on both the ground floor and the first
floor of the building. From the fan a number of main headers
are tied in. At the point of use a four inch PVC duct stems
from the main header which is then connected to a six inch
neederman head unit which provides flexibility of use to the
operator. The minimum face velocity required form each
point is 0.5 m/s.
The fire alarm system in the BCP plant is an L1/M Analogue
Addressable Fire Alarm System. This comprises of IP and I.S.
Heat detector heads in the production areas and IP and I.S.
rated Smoke detectors in the non process areas. All exits
have a break glass unit just inside them and there are break
glass units within 30 m of any operator.
The Fire Sprinkler system in the building is fed from the
main water supply to the site. Again all areas of the
building have sprinkler head protection suitably located
which are inspected by the insurance people on at least an
annual basis. Integrated into the sprinkler system is a foam
tank which draws foam into and mixes with water to provide
further protection.
Storage: Store in cold, dry and dark places; keep container tightly
closed when not in use.
Packaging of the substance and or preparation: The substance is transported in 25 kg HDPE drums.
Transport information
Shippingopen allclose all
SpecialProvisionsopen allclose all
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Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
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Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
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Special provisions / remarks
- Remarks:
- Transport: not regulated
SpecialProvisionsopen allclose all
Exposure controls / personal protection
Stability and reactivity
Danger other than fire: not known
Chemical reaction with water: Not hazardous (see related Chilworth study no. J13564)
Dust explosion: Not known
Dust explosion determined by test: N
Disposal considerations
Industry - Possibility of recovery/recycling: Recovery offsite
Industry - Possibility of neutralisation: none
Industry - Possibility of destruction - incineration: Recommended
Industry - Possibility of destruction - water purification: Not applicable
Industry - Possibility of destruction - other: Not known
Public at large - Possibility of recovery/recycling: Not applicable
Public at large - Possibility of neutralisation: Not applicable
Public at large - Possibility of destruction: controlled discharge: Not applicable
Public at large - Possibility of destruction - incineration: Not applicable
Public at large - Possibility of destruction - water purification: Not applicable
Public at large - Possibility of destruction - others: Not known
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.