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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

Isopropyl acetate is practically non-toxic to invertebrates.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
1 260 mg/L

Marine water invertebrates

Marine water invertebrates
Effect concentration:
110 mg/L

Additional information

In a 48 hour acute toxicity study, Artemia Salina (Brine shrimp) were exposed to isopropyl acetate at concentrations up to 1,000 mg/l under static conditions. The EC50 (mobility) was established at 110 mg/l. Based on the results of this study, this substance would be not be classified toxic to the environment according to the classification system of the EU (CLP).

In a 24 hour acute toxicity study, Daphnia magna were exposed to ethyl acetate at nominal concentrations which produced a range of responses from 0 to 100% immobility under static conditions. An EC50 of 1260mg/l was established. Based on the results of this study, this substance would not be classified toxic to the environment according to the classification system of the EU (CLP).