Registration Dossier
Registration Dossier
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EC number: 616-248-3 | CAS number: 75627-31-5
Endpoint summary
Administrative data
Description of key information
Additional information
The aquatic ecotoxicity database for nonylphenol ethoxylate, sarcosine derivative (CAS number 75627-31-5) is limited to an acute toxicity study with Daphnia magna, an algae toxicity study with Desmodesmus subspicatus and a micro-organisms respiration inhibition study with sewage sludge. Read-across has been used to assess the toxicity to fish and as supporting information for the toxicity to Daphnia.
Further ecotoxicity testing is not proposed because the chemical safety assessment does not indicate the need to investigate further the effects on aquatic organisms. Exposure of the aquatic environment is unlikely as emissions to the environment do not occur from the only manufacturing site and the substance is not marketed within the EU. Therefore long term toxicity testing with fish has been waived to avoid further vertebrate testing.
The table provides an overview of the ecotoxicity data used for the hazard assessment of nonylphenol ethoxylate sarcosinate derivative.
Result |
Remarks |
Reference |
|
Oncorhynchus mykiss OECD 203 |
96h-LC50 = 1.3 mg/L |
Read-across, Reliability 2, Nominal conc. |
Wetton, 1996 |
Oncorhynchus mykiss OECD215 |
28d-NOEC = 0.1 mg ai/L 28d-LOEC = 0.18 mg ai/L |
Read-across, Reliability 2 Nominal conc. |
Wetton, 1992 |
Daphnia magna OECD 202 |
48h-EC50 = 3.92 mg ai/L |
Reliability 1 Measured concentration |
Noack, 2013 |
Daphnia magna OECD 202 |
48h-LC50 = 1.8 mg ai/L |
Read-across Reliability 2 Nominal conc. |
Wetton, 1996 |
Daphnia magna 21d OECD 202 (1984) |
21d-NOEC = 0.18 mg ai/L
|
Read-across Reliability 2 Nominal conc. |
Wetton, 1999 |
Desmodesmus subspicatus OECD 201 |
72h-ErC50 > 10.2 mg ai/L 72h-ErC10 = 5.13 mg ai/L |
Reliability 1 Measured concentration |
Scheerbaum, 2012 |
Microorganisms OECD 209
|
3h-EC50 = 421 mg ai/L 3h-EC10 =57.4 mg ai/L |
Reliability 1 Nominal conc.
|
Fiebig, 2012 |
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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