Registration Dossier
Registration Dossier
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EC number: 405-820-6 | CAS number: 30025-38-8
Developmental toxicity / teratogenicity
Administrative data
- Endpoint:
- developmental toxicity
- Type of information:
- read-across based on grouping of substances (category approach)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Justification for type of information:
- See category justification document attached separately
Data source
Materials and methods
Test material
- Reference substance name:
- -
- EC Number:
- 405-820-6
- EC Name:
- -
- Cas Number:
- 30025-38-8
- Molecular formula:
- C8H18O3
- IUPAC Name:
- reaction mass of 5-methyl-4,7-dioxa-2-nonanol and 6-methyl-4,7-dioxa-2-nonanol
- Reference substance name:
- Dipropylene Glycol Monoethyl Ether
- IUPAC Name:
- Dipropylene Glycol Monoethyl Ether
- Details on test material:
- - Name of test material (as cited in study report): Ethoxypropoxy Propanol (synonym of Dipropylene glycol monoethyl ester).
- Physical state: A clear colourless liquid
- Analytical purity: Not specified
- Impurities (identity and concentrations): Not specified
Purity test date: Not specified
- Lot/batch No. GOHC laboratory Sample No. 1030, Oil Stock Ref. No. 09977, 134/109
- Expiration date of the lot/batch: Not specified
- Stability under test conditions: Not specified.
- Storage condition of test material: At ambient temperature in brown screw-capped bottle.
- Other: None
Constituent 1
Constituent 2
Test animals
- Species:
- rat
Administration / exposure
- Route of administration:
- inhalation
Results and discussion
Results: maternal animals
Effect levels (maternal animals)
- Dose descriptor:
- NOAEC
- Effect level:
- 100 ppm
- Based on:
- test mat.
- Basis for effect level:
- body weight and weight gain
Maternal abnormalities
- Abnormalities:
- no effects observed
Results (fetuses)
Effect levels (fetuses)
- Dose descriptor:
- NOAEC
- Based on:
- test mat.
- Sex:
- male/female
- Remarks on result:
- not determinable due to absence of adverse toxic effects
- Remarks:
- based on extrapolation from source substance and taking into account vapour pressure of target substance.
Fetal abnormalities
- Abnormalities:
- no effects observed
Overall developmental toxicity
- Developmental effects observed:
- no
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
