Registration Dossier
Registration Dossier
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EC number: 203-756-1 | CAS number: 110-31-6
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (72 h) > 0.053 mg/L for Pseudokircheneriella subcapitata (OECD 201, limit test)
Key value for chemical safety assessment
Additional information
There is no data available on the toxicity to algae potential of Amides, C16 and C18-C20 (even numbered, unsaturated), N,N’-ethylenebis. In order to fulfil the standard information requirements set out in Annex VII, 9.1.2, in accordance with Annex XI, 1.5, of Regulation (EC) No 1907/2006, read-across from a structurally related substance is conducted.
A detailed justification for the grouping of chemicals and read-across is provided in Sections 6.1 and 13.
The toxicity of Amides, C16 and C18-C20 (even numbered, unsaturated), N,N’-ethylenebis to algae was investigated in a read across approach using data from the structural analogue Amides, C16-C18 (even), N,N'-ethylenebis. The toxicity of the test item to the freshwater algae Pseudokircheneriella subcapitata was investigated in one key study from the Japanese Ministry of Environment (MOE, 2002). This test was conducted according to OECD 201. Algae were exposed for 72 h to a limit concentration of nominal 100 mg/L (corresponding to 0.0053 mg/L measured concentration). The results from this test show that after 72 h exposure to Amides, C16-C18 (even), N,N'-ethylenebis no effects on growth rate of Pseudokircheneriella subcapitata were observed up to the highest attainable concentration (0.053 mg/L, limit of solubility). Therefore, the EC50 and the NOEC (72 h) were > 0.053 mg/L, and no toxicity within the range of water solubility was reported.
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