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Diss Factsheets
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EC number: 248-502-0 | CAS number: 27503-81-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- from Sep. 18, 1989 to Nov. 15, 1989
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
- Remarks:
- OECD guidline test with GLP, but no purity given
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- GLP compliance:
- yes
- Analytical monitoring:
- yes
- Details on sampling:
- daily
- Vehicle:
- no
- Details on test solutions:
- The weight of the substance in water was stirred on a magnetic stirrer for about 24 hours (milky opaque suspension). At neutralization becoming necessary at the start of test, the result was an almost full solution. After 24 hours no substance residues were visible any longer.
- Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
- Details on test organisms:
- Origin: West Aquarium (Bad Lauterberg)
Date of birth: June 08, 1989
Date of delivery: Aug. 31, 1989
Length: 2.5 - 3.5 cm
Maintenance or dilution water: synthetic sweet water acc. to ISO - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 96 h
- Hardness:
- 12.5 dH
- Test temperature:
- 22.2 - 22.6 °C
- pH:
- 6.9 - 7.2
- Dissolved oxygen:
- 87.1 - 96.0 %
7.4 - 8.1 mg/L - Salinity:
- Calcium/Magnesium ratio was 68.0 mg/L / 11.0 mg/L
- Nominal and measured concentrations:
- nominal: 10000 mg/L
measured: ± 20 % - Details on test conditions:
- Test aquariums 300×135×200 mm
5 L test medium
areated
Method of application: direct weighing-in of the sample - Reference substance (positive control):
- no
- Key result
- Duration:
- 96 h
- Dose descriptor:
- LC0
- Effect conc.:
- >= 10 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- No mortality happened at the test duration of 96 h at the concentration of 10000 mg/L and control.
- Validity criteria fulfilled:
- yes
- Conclusions:
- The LC0 was >= 10000 mg/L (nominal conc.) based on the test result. The LC50 was determined to be >= 10000 mg/L (nominal conc.).
- Executive summary:
The test was performed to determine the acute toxicity on fish of test substance according to OECD 203 under GLP compliance. The test concentration of 10000 mg/L was set with a control. The test result showed no mortality happened at the test duration of 96 h at the concentration of 10000 mg/L and control. Thus, the LC0 was >= 10000 mg/L (nominal conc.) based on the test result.
Reference
Description of key information
The short-term toxicity to fish was determined in an OECD guideline study.The LC0 value was determined to be >= 10000 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Dose descriptor:
- LC50
- Effect concentration:
- > 10 000 mg/L
Additional information
The available acute fish test was performed according to OECD 203 under GLP compliance. The test concentration of 10000 mg/L was set with a control. The test result showed no mortality happened at the test duration of 96 h at the concentration of 10000 mg/L and control. Thus, the LC0 was >= 10000 mg/L (nominal conc.) based on the test result.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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