Registration Dossier
Registration Dossier
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EC number: 217-218-9 | CAS number: 1779-49-3
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- Quaternary (triphenyl-) phosphonium compounds: Environmental behavior and toxicity
- Author:
- Simon Brand, Michael P. Schlüsener, Dinah Albrecht, Uwe Kunkel, Claudia Strobel, Tamara Grummt, Thomas A. Ternes
- Year:
- 2 018
- Bibliographic source:
- Water Research 136 (2018) 207-219
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Version / remarks:
- 1995
- Principles of method if other than guideline:
- Octanol/water partition coefficient was determined according to the OECD guideline 107 (shake flask method), with some adaptations. In a 10mL graduated flask, 10mL of n-octanol saturated ultra-pure water were spiked with 50 µL of analyte stock solution (conc. 10 µg/mL in water) and overlaid with 0.5 mL (1 mL, 0.25 mL) of n-octanol. Samples were stirred furiously over 3 h with a magnetic stirrer, so that a vortex inside the flask would develop and both phases could mix. At the start and the end of stirring, flasks were additionally shaken thoroughly by bare hands. Phases were then allowed to separate over 24 h.
- GLP compliance:
- not specified
- Type of method:
- flask method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- Methyltriphenylphosphonium bromide
- EC Number:
- 217-218-9
- EC Name:
- Methyltriphenylphosphonium bromide
- Cas Number:
- 1779-49-3
- Molecular formula:
- C19H18P.Br
- IUPAC Name:
- methyl(triphenyl)phosphonium bromide
- Test material form:
- solid
Constituent 1
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source: Sigma-Aldrich
- Purity: 98%
Study design
- Analytical method:
- liquid chromatography
- mass spectrometry
Results and discussion
Partition coefficient
- Type:
- log Pow
- Partition coefficient:
- -1.18
- Remarks on result:
- other: logDow
- Remarks:
- -1.18 (+/-0.21)
- Details on results:
- Charge is independent of pH
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
