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EC number: 400-410-3 | CAS number: 25485-88-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to soil macroorganisms except arthropods
Administrative data
- Endpoint:
- toxicity to soil macroorganisms except arthropods: short-term
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1993
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 993
- Report date:
- 1993
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 207 (Earthworm, Acute Toxicity Tests)
- GLP compliance:
- yes
Test material
- Reference substance name:
- Cyclohexyl Salicylate
- IUPAC Name:
- Cyclohexyl Salicylate
- Details on test material:
- Cyclohexyl Salicylate Lot No. SAT 921176/1096, Purity 98%
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test substrate
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Eisenia fetida
- Animal group:
- annelids
Study design
- Study type:
- laboratory study
- Substrate type:
- natural soil
- Limit test:
- no
- Total exposure duration:
- 14 d
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 14 d
- Dose descriptor:
- LC50
- Effect conc.:
- > 560 - < 1 000 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Duration:
- 14 d
- Dose descriptor:
- LC0
- Effect conc.:
- 560 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
Any other information on results incl. tables
No Earthworm mortality was observed at concentrations up to and including 560 mg test substance/kg dry weight soil. Total mortality at the 1000 mg/kg dry weight soil test concentration was 60% on Day 7, and, remained at this level til the end of the study. The LC50 is situated between 560 and 1000 mg test substance/kg dry weight soil. The LC0 is 560 mg test substance/kg dry weight soil. No significant weight loss was observed up to and including 560 mg test substance/kg dry weight soil test concentration. Chloracetamide demonstrated an LC0 and LC100 of, respectively, 10 and 100 mg Chloracetamide/kg dry weight soil.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Executive summary:
The toxicity of CYCLOHEXYL SALICYLATE to the earthwormEisenia fetidaandrei over an exposure period of 14 Days. Following a range.finder test, the definitive test was set-up with 5 test concentrations (94, 170, 310, 560 and 1000 mg test substance/kg dry weight soil) and a Control. Soil was maintained in 2 L containers with air-flow through covers. Adult earthworms of at least 3 Months old were introduced in to the soil. Samples were examined for mortality and other observable effects (mucous secretion, weariness, loss of weight) on Day 7 and Day 14. Soil moisture was 25.6% (prior to test substance addition) at the beginning and 26.4% at the end of the study. Soil pH was 6.5, and the incubation temperature ranged from 21.5 °C to 22.0 °C. Chloracetamide was employed as the toxicity reference substance.
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