Registration Dossier
Registration Dossier
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EC number: 205-538-1 | CAS number: 142-47-2
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The EC50 for growth rate reduction (ERC50: 0-72h) was beyond the range tested, i.e. exceeded a TWA concentration of 2.0 mg/l.
The NOEC for growth rate reduction was 0.24 mg/l based on TWA concentrations.
The EC10 (0 -72 h) for growth rate reduction was calculated to be 1.3 mg/L based on TWA concentrations.
Key value for chemical safety assessment
- EC10 or NOEC for freshwater algae:
- 1.3 mg/L
Additional information
A study was performed according to OECD Guideline 201/ EU method C.3 and GLP guidelines.Under the conditions of the test, L-Glutamate monohydrate reduced growth rate of the fresh water algae species significantly at a TWA concentration of 1.0 mg/l and higher. The EC50 for growth rate reduction (ERC50: 0-72h) was beyond the range tested, i.e. exceeded a TWA concentration of 2.0 mg/l. The NOEC for growth rate reduction was 0.24 mg/l based on TWA concentrations. As preference is given to the EC10 over a NOEC value (Guidance on the Application of the CLP Criteria, Version 4.0 (November 2013), section 4.1.3.1.1., footnote 88), the EC10 (0 -72 h) for growth rate reduction was calculated to be 1.3 mg/L based on TWA concentrations.
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