Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 617-251-2 | CAS number: 816431-72-8
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 26 Jul - 27 Jul 2006
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Version / remarks:
- 1995
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Version / remarks:
- 92/69
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: vapour pressure balance
- Temp.:
- 20 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: The calculated vapour pressure values are extrapolated
- Key result
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: The calculated vapour pressure values are extrapolated
- Temp.:
- 50 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: The calculated vapour pressure values are extrapolated
- Conclusions:
- The vapour pressure of the test substance at 20, 25 and 50 °C corresponds to 2.4e-8 Pa, 6.0E-8 Pa and 3.8e-6 Pa, respectively.
- Executive summary:
In a GLP study according to 92/69/EEC Method A4 and OECD 104, the vapour pressure of the test substance was determined using the Vapour Pressure Balance (Effusion Method). The vapour pressure was measured in the temperature range of 35 °C to 149 °C. Above 109 °C, a vapour pressure could be measured. The values for 20, 25 and 50 °C are calculated, using the Antoine constants A, B and C as 2.4e-8 Pa, 6.0E-8 Pa and 3.8e-6 Pa, respectively.
Reference
Validity criteria for the measurement of vapour pressure:
| Target condition according to guideline: | Actual condition according to the study: | Validity criteria met: |
| The vapour pressure should be determined for at least two temperatures. Three or more are preferred in the range 0 to 50 °C, in order to check the linearity of the vapour pressure curve. | Three values are available at 20, 25 and 50 °C | Yes |
| A log p versus 1 /T curve should be stated. | A curve for log vapour pressure against 1/T is available | Yes |
| An estimate of the vapour pressure at 20 or 25 °C should be stated. | The estimated vapor pressure at 20, 25 °C were given. | Yes |
Description of key information
In a GLP study according to 92/69/EEC Method A4 and OECD 104, the vapour pressure of the test substance was determined using the Vapour Pressure Balance (Effusion Method). The vapour pressure was measured in the temperature range of 35 °C to 149 °C. Above 109 °C, a vapour pressure could be measured. The values for 20, 25 and 50 °C are calculated, using the Antoine constants A, B and C as 2.4e-8 Pa, 6.0E-8 Pa and 3.8e-6 Pa, respectively.
Key value for chemical safety assessment
- Vapour pressure:
- 0 Pa
- at the temperature of:
- 25 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
