Registration Dossier
Registration Dossier
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EC number: 955-780-3 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Hydrolysis: On the basis of the experimental studies of the structurally similar read across chemical and applying the weight of evidence approach and by evaluating the hydrolysis of test chemical in water, the half-life, DT50 value of test chemical was found to be > 1 to < 46 years at pH 4 to 9 and temperature of 25°C.
Additional information
Hydrolysis:
Data available of the structurally similar read across chemicals has been reviewed to determine the hydrolysis of test chemical in water. The studies are as mentioned below:
The first study of hydrolysis was carried out for test chemical in water. The half-life, DT50 value of test chemical was found to be 46 years at pH 7 and temperature of 25°C. On the basis of result the test chemical was found to be stable in water.
The second study of hydrolysis was carried out for test chemical in water. The half-life, DT50 value of test chemical was found to be > 1 year at pH 4 to 9. On the basis of result the test chemical was found to be stable in water.
The third study of hydrolysis was carried out by Directive 84/449/EEC, C.10. The test was performed at pH 4, 7, and 9 and a temperature of 50 °C. Analytical monitoring of test substance was done by HPLC using an external standard. The buffered aqueous solutions were heated at 121 °C for 15 min before use to assure sterility. The exclusion of photolytic effects was done by using brown glass reaction flasks. The half-life, DT50 value of test chemical was found to be > 1 year at pH 4, 7 and 9 and a temperature of 25 °C. On the basis of result, the test chemical was found to be stable in water.
On the basis of the experimental studies of the structurally similar read across chemical and applying the weight of evidence approach and by evaluating the hydrolysis of test chemical in water, the half-life, DT50 value of test chemical was found to be > 1 to < 46 years at pH 4 to 9 and temperature of 25°C. On the basis of result the test chemical was found to be stable in water
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