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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
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- Endpoint summary
- Stability
- Biodegradation
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- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
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- Specific investigations
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- Additional toxicological data
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- May - July 2020
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Version / remarks:
- March 2006
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: Knudsen cell
- Specific details on test material used for the study:
- Appearance: white powder
- Test no.:
- #1
- Temp.:
- 60 °C
- Vapour pressure:
- 0.015 Pa
- Test no.:
- #2
- Temp.:
- 75 °C
- Vapour pressure:
- 0.048 Pa
- Test no.:
- #3
- Temp.:
- 90 °C
- Vapour pressure:
- 0.152 Pa
- Test no.:
- #4
- Temp.:
- 20 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: calculated from #1 - #3
- Test no.:
- #5
- Temp.:
- 25 °C
- Vapour pressure:
- 0.001 Pa
- Remarks on result:
- other: calculated from #1 - #3
- Conclusions:
- Vapour pressure for AM(pfa)4 at 20 °C: 0.000330 (3.30 * 10E-04) Pa and at 25 °C: 0.000561 (5.61 * 10E-04) Pa
- Executive summary:
The vapour pressure of the test item AM(pfa)4 was determined at eight different temperatures (30, 45, 60, 75, 90, 105, 120 and 135 °C) according to OECD 104 resp. EU A.4 using the effusion method (weight loss). Experiment 1 – 2 and 6 - 8 (nominal temperature 30 - 45 °C and 105 – 135 °C) showed no reproducible weight loss and were not used for calculation. When visible contaminations, caused by explosive evaporation of the test item, were observed, the cells were meticulously cleaned and weighed. This weight was used as initial weight for the subsequent measurements. To avoid bias, these measurements were not used for calculations.
Three experiments could be evaluated as they showed relevant and reproducible weight loss. All evaluated experiments showed good repeatability, giving relative standard deviations of less than 26.4 % (limit value from the guideline 30 %) and good correlation. Therefore, the result of the test can be considered valid.
For the test item AM(pfa)4, the following vapour pressures at 20 °C and at 25 °C were calculated from the regression equation established in this experiment:
Vapour pressure at 20 °C: 3.30 * 10-04 Pa
Vapour pressure at 25 °C: 5.61 * 10-04 Pa
Reference
FINDINGS
Sample Weights
The mass of sample in the respective cell is presented in the following table:
Table 1 a: Sample Weights
Parameter | Cell empty | Cell + test item | Cell + test item + cap | Test item |
Unit | g | g | g | g |
Knudsen-cell 1 | 2.57017 | 4.17170 | 4.38327 | 1.60153 |
Knudsen-cell 2 | 2.55472 | 4.04749 | 4.26063 | 1.49277 |
Knudsen-cell 3 | 2.55455 | 3.99813 | 4.21122 | 1.44358 |
Knudsen-cell 4 | 2.55702 | 3.95784 | 4.16966 | 1.40082 |
Measurement Data
The data of the evaluated experiments is presented in the following tables:
Table 2 a: Measurement Data Experiment 1, Nom. Temperature 30 °
Date and time START | 12.05.2020 14:20 | 13.05.2020 13:30 | 14.05.2020 13:50 |
Date and time END | 13.05.2020 12:30 | 14.05.2020 12:40 | 15.05.2020 11:15 |
Parameter | Weight m | Weight m | Weight m |
Unit | g | g | g |
Knudsen-cell 1 | 4.29135 | 4.22722 | 4.21435 |
Knudsen-cell 2 | 4.16343 | 4.09634 | 4.08237 |
Knudsen-cell 3 | 4.11970 | 4.05587 | 4.04103 |
Knudsen-cell 4 | 4.08352 | 4.02395 | 4.01378 |
Table 2 b: Measurement Data Experiment 2, Nom. Temperature 45 °C
Date and time START | 18.05.2020 11:45 | 19.05.2020 11:20 | 25.05.2020 08:45 |
Date and time END | 19.05.2020 10:00 | 20.05.2020 12:40 | 26.05.2020 09:20 |
Parameter | Weight m | Weight m | Weight m |
Unit | g | g | g |
Knudsen-cell 1 | 4.12297 | 4.11948 | 4.08572 |
Knudsen-cell 2 | 3.99163 | 3.97401 | 3.93667 |
Knudsen-cell 3 | 3.95363 | 3.94854 | 3.93293 |
Knudsen-cell 4 | 3.96229 | 3.93129 | 3.90187 |
Table 2 c; Measurement Data Experiment 3, Nom. Temperature 60 °
Date and time START | 26.05.2020 14:05 | 27.05.2020 13:35 | 28.05.2020 14:50 |
Date and time END | 27.05.2020 12:45 | 28.05.2020 13:50 | 29.05.2020 11:10 |
Parameter | Weight m | Weight m | Weight m |
Unit | g | g | g |
Knudsen-cell 1 | 4.07604 | 4.06781 | 4.06284 |
Knudsen-cell 2 | 3.91779 | 3.91523 | 3.90959 |
Knudsen-cell 3 | 3.92102 | 3.91809 | 3.91143 |
Knudsen-cell 4 | 3.85322 | 3.84149 | 3.83264 |
Table 2 d: Measurement Data Experiment 4, Nom. Temperature 75 °C
Date and time START | 02.06.2020 09:15 | 03.06.2020 12:10 | 04.06.2020 13:45 |
Date and time END | 03.06.2020 11:05 | 04.06.2020 13:00 | 05.06.2020 13:00 |
Parameter | Weight m | Weight m | Weight m |
Unit | g | g | g |
Knudsen-cell 1 | 3.17168 | 3.13818 | 3.12270 |
Knudsen-cell 2 | 3.15542 | 3.11957 | 3.10135 |
Knudsen-cell 3 | 3.12599 | 3.10068 | 3.08693 |
Knudsen-cell 4 | 3.12911 | 3.10160 | 3.08124 |
Table 2 e: Measurement Data Experiment 5, Nom. Temperature 90 °C
Date and time START | 08.06.2020 10:10 | 09.06.2020 10:20 | 16.06.2020 10:40 |
Date and time END | 09.06.2020 09:20 | 10.06.2020 12:45 | 17.06.2020 12:50 |
Parameter | Weight m | Weight m | Weight m |
Unit | g | g | g |
Knudsen-cell 1 | 3.06560 | 3.04546 | 2.96818 |
Knudsen-cell 2 | 3.03502 | 3.02278 | 2.94860 |
Knudsen-cell 3 | 3.01923 | 3.00500 | 2.92959 |
Knudsen-cell 4 | 3.02415 | 3.00805 | 2.92838 |
Table 2 f: Measurement Data Experiment 6, Nom. Temperature 105 °C
Date and time START | 17.06.2020 13:40 | 22.06.2020 10:30 | 23.06.2020 12:00 |
Date and time END | 18.06.2020 12:45 | 23.06.2020 11:00 | 24.06.2020 11:20 |
Parameter | Weight m | Weight m | Weight m |
Unit | g | g | g |
Knudsen-cell 1 | 2.95687 | 2.94359 | 2.94101 |
Knudsen-cell 2 | 2.94000 | 2.92762 | 2.92510 |
Knudsen-cell 3 | 2.92064 | 2.90959 | 2.90745 |
Knudsen-cell 4 | 2.91939 | 2.90704 | 2.90439 |
Table 2 g: Measurement Data Experiment 7, Nom. Temperature 120 °C
Date and time START | 24.06.2020 11:55 | 29.06.2020 11:30 | 30.06.2020 12:00 |
Date and time END | 25.06.2020 13:20 | 30.06.2020 11:15 | 01.07.2020 14:15 |
Parameter | Weight m | Weight m | Weight m |
Unit | g | g | g |
Knudsen-cell 1 | 2.93718 | 2.92906 | 2.92762 |
Knudsen-cell 2 | 2.92145 | 2.91394 | 2.91241 |
Knudsen-cell 3 | 2.90399 | 2.89700 | 2.89538 |
Knudsen-cell 4 | 2.90111 | 2.89400 | 2.89254 |
Table 2 h: Measurement Data Experiment 8, Nom. Temperature 135 °C
Date and time START | 01.07.2020 14:45 | 02.07.2020 12:00 | 06.07.2020 10:45 |
Date and time END | 02.07.2020 11:30 | 03.07.2020 10:30 | 07.07.2020 09:10 |
Parameter | Weight m | Weight m | Weight m |
Unit | g | g | g |
Knudsen-cell 1 | 2.92487 | 2.92446 | 2.92444 |
Knudsen-cell 2 | 2.90980 | 2.90974 | 2.90975 |
Knudsen-cell 3 | 2.89301 | 2.89301 | 2.89302 |
Knudsen-cell 4 | 2.89011 | 2.89009 | 2.89008 |
Observations
At 60 °C: At the first measurement of experiment 3, all cells were slightly contaminated. Therefore, the cells were meticulously cleaned and weighed. This weight was used as initial weight for the subsequent measurements. To avoid bias, this measurement was not used for calculations.
At 60 °C: At the third measurement of experiment 3, the first cell were slightly contaminated. Therefore, the cell was meticulously cleaned and weighed. This weight was used as initial weight for the subsequent measurements. To avoid bias, this measurement was not used for calculations.
At 75 °C: At the first measurement of experiment 4, all cells were slightly contaminated. Therefore, the cells were meticulously cleaned and weighed. This weight was used as initial weight for the subsequent measurements. To avoid bias, this measurement was not used for calculations.
At 75 °C: At the second measurement of experiment 4, the first and the second cells were slightly contaminated. Therefore, the cells were meticulously cleaned and weighed. This weight was used as initial weight for the subsequent measurements. To avoid bias, this measurement was not used for calculations.
At 90 °C: At the second measurement of experiment 5, all cells were slightly contaminat-ed. Therefore, the cells were meticulously cleaned and weighed. This weight was used as initial weight for the subsequent measurements. To avoid bias, this measurement was not used for calculations.
CALCULATION OF RESULTS
The vapour pressure was calculated using the following equation: p = m/KAtѴ(2πRT/M)
with
p = vapour pressure in Pa (to be calculated)
m = weight loss in kg (value given in tables above divided by 1000)
T = time in s (as given in tables above)
A = area of aperture in m² (7.85 * 10E-7 m² for d = 1 mm)
K = correction factor (0.909)
R = universal gas constant in J/Mol*K (8.314472)
T = temperature in K (as given in tables above)
M = molecular weight in kg/Mol (0.974)
The correction factor depends on the relation length/radius of the aperture of the Knudsen cell. The following factor is stated in the literature: Relation 0.2, K 0.909 (E.D.Cater, Ch.2A, Physicochem. Measurements in Metal Research, Part 1, R.A. Rapp, Ed., John Wiley, New York, 1970). With the chosen length of the aperture 0.1 mm and the chosen radius 0.5 mm, a relation of 0.2 was calculated, and a correction factor of 0.909 was chosen.
Calculation Results
All calculation results are given in the tables below.
In all tables, E-0X represents multiplication with 10-X. Experiment 1 - 2 and 6 - 8 (nominal temperature 30 – 45 and 105 - 130 °C) showed no reproducible weight loss. Therefore, they were not used for calculation.
Table 3 a: Calculation Results Experiment 3, Temperature in K 333.2 (60.0 °C)
Date of Measurement | 27.05.2020 12:45 | 28.05.2020 13:50 | 29.05.2020 11:10 | ||||||
Elapsed Time in s | 81600 | 87300 | 73200 | ||||||
Parameter | Weight loss | to be used | Vapour pressure | Weight loss | to be used | Vapour pressure | Weight loss | to be used | Vapour pressure |
Unit | g | yes/no | Pa | g | yes/no | Pa | g | yes/no | Pa |
Knudsen-cell 1 | 0.00968 | yes | 2.22E-02 | 0.00823 | yes | 1.77E-02 | 0.00497 | yes | 1.27E-02 |
Knudsen-cell 2 | 0.01888 | yes | 4.33E-02 | 0.00256 | yes | 5.49E-03 | 0.00564 | yes | 1.44E-02 |
Knudsen-cell 3 | 0.01191 | yes | 2.73E-02 | 0.00293 | yes | 6.28E-03 | 0.00666 | yes | 1.70E-02 |
Knudsen-cell 4 | 0.04865 | yes | 1.12E-01 | 0.01173 | yes | 2.52E-02 | 0.00885 | yes | 2.26E-02 |
Mean |
| no |
|
| yes | 1.36E-02 |
| yes | 1.67E-02 |
Standard deviation: |
|
|
|
|
| 9.47E-03 |
|
| 4.34E-03 |
Mean of measured values: |
| 1.518E-02 |
|
|
|
|
|
|
|
Standard deviation: |
| 2.162E-03 | RSD: |
| 14.2% |
|
|
|
|
If “no” is stated in the respective column: measurement was not considered for the calculation of the mean.
Table 3 b: Calculation Results Experiment 4, Temperature in K 348.2 (75.0 °C)
Date of Measurement | 03.06.2020 11:05 | 04.06.2020 13:00 | 05.06.2020 13:00 | ||||||
Elapsed Time in s | 93000 | 89400 | 83700 | ||||||
Parameter | Weight loss | to be used | Vapour pressure | Weight loss | to be used | Vapour pressure | Weight loss | to be used | Vapour pressure |
Unit | g | yes/no | Pa | g | yes/no | Pa | g | yes/no | Pa |
Knudsen-cell 1 | 0.89116 | yes | 1.83E+00 | 0.03350 | no |
| 0.01548 | yes | 3.54E-02 |
Knudsen-cell 2 | 0.75417 | yes | 1.55E+00 | 0.03585 | no |
| 0.01822 | yes | 4.17E-02 |
Knudsen-cell 3 | 0.78544 | yes | 1.62E+00 | 0.02531 | yes | 5.42E-02 | 0.01375 | yes | 3.14E-02 |
Knudsen-cell 4 | 0.70353 | yes | 1.45E+00 | 0.02751 | yes | 5.89E-02 | 0.02036 | yes | 4.66E-02 |
Mean |
| no |
|
| yes | 5.65E-02 |
| yes | 3.88E-02 |
Standard deviation: |
|
|
|
|
| 3.33E-03 |
|
| 6.69E-03 |
Mean of measured values: |
| 4.766E-02 |
|
|
|
|
|
|
|
Standard deviation: |
| 1.257E-02 | RSD: |
| 26.4% |
|
|
|
|
If “no” is stated in the respective column: measurement was not considered for the calculation of the mean.
Table 3 c: Calculation Results Experiment 5, Temperature in K 363.2 (90.0 °C)
Date of Measurement | 09.06.2020 09:20 | 10.06.2020 12:45 | 17.06.2020 12:50 | ||||||
Elapsed Time in s | 83400 | 95100 | 94200 | ||||||
Parameter | Weight loss | to be used | Vapour pressure | Weight loss | to be used | Vapour pressure | Weight loss | to be used | Vapour pressure |
Unit | g | yes/no | Pa | g | yes/no | Pa | g | yes/no | Pa |
Knudsen-cell 1 | 0.05710 | yes | 1.34E-01 | 0.02014 | yes | 4.14E-02 | 0.07728 | yes | 1.60E-01 |
Knudsen-cell 2 | 0.06633 | yes | 1.55E-01 | 0.01224 | yes | 2.52E-02 | 0.07418 | yes | 1.54E-01 |
Knudsen-cell 3 | 0.06770 | yes | 1.59E-01 | 0.01423 | yes | 2.93E-02 | 0.07541 | yes | 1.57E-01 |
Knudsen-cell 4 | 0.05709 | yes | 1.34E-01 | 0.01610 | yes | 3.31E-02 | 0.07967 | yes | 1.65E-01 |
Mean |
| yes | 1.45E-01 |
| no |
|
| yes | 1.59E-01 |
Standard deviation: |
|
| 1.35E-02 |
|
|
|
|
| 4.96E-03 |
Mean of measured values: |
| 1.523E-01 |
|
|
|
|
|
|
|
Standard deviation: |
| 9.603E-03 | RSD: |
| 6.3% |
|
|
|
|
If “no” is stated in the respective column: measurement was not considered for the calculation of the mean.
Evaluation
The measured values for temperature and vapour pressure were evaluated as follows:
Table 4: Evaluation of Calculated Values
Parameter | T | Mean p | 1/T | log p |
Unit | K | Pa | 1/K | log Pa |
Values | 333.2 | 1.52E-02 | 3.0012E-03 | -1.8189 |
| 348.2 | 4.77E-02 | 2.8719E-03 | -1.3219 |
| 363.2 | 1.52E-01 | 2.7533E-03 | -0.8174 |
In this table, E-0X represents multiplication with 10-X.
Since the values were correlated by a linear relation, the data could be fitted by linear regression.
Table 4: Parameters of Linear Regression
Parameter | Value |
Slope | -4036.8 |
Intercept | 10.2882 |
Correlation Coefficient r | -0.9996 |
Coefficient of Determination r² | 0.9992 |
RESULTS
The following vapour pressures were determined experimentally and considered as valid (mean and standard deviation given):
Table 5: Experimentally Determined Vapour Pressures
T | T | p | Stand. Dev. p | RSD p |
°C | K | Pa | Pa | % |
60.0 | 333.2 | 1.52E-02 | 2.16E-03 | 14.2% |
75.0 | 348.2 | 4.77E-02 | 1.26E-02 | 26.4% |
90.0 | 363.2 | 1.52E-01 | 9.60E-03 | 6.3% |
In this table, E-0X represents multiplication with 10-X.
Stand. Dev. = Standard Deviation; RSD = Relative Standard Deviation
For the test item AM(pfa)4, the following vapour pressures at 20 °C and at 25 °C were calculated from the regression equation:
Vapour pressure at 20 °C: 3.30 * 10-04 Pa
Vapour pressure at 25 °C: 5.61 * 10-04 Pa
The linear regression of log p vs. 1/T gave a correlation coefficient r of - 0.9996, showing good repeatability and precision. Therefore, the determination is considered as valid.
Positive Control: For Diethylphthalate the following vapour pressure was determined and compared with recommended value: Vapour pressure (positive control) at 30 °C: 1.96*10-1 Pa
Criterion for the vapour pressure of the positive control at 30 °C: 0.44*10-1 - 2.44*10-1 Pa
The vapour pressure met the validity criteria. Therefore, the study can be considered as valid.
Description of key information
Vapour pressure for AM(pfa)4 at 20 °C: 0.000330 (3.30 * 10E-04) Pa and at 25 °C: 0.000561 (5.61 * 10E-04) Pa
Key value for chemical safety assessment
- Vapour pressure:
- 0 Pa
- at the temperature of:
- 20 °C
Additional information
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