Registration Dossier
Registration Dossier
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EC number: 951-575-8 | CAS number: -
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 06/04/2020 to 29/05/2020
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- other: EU Method A.8 - Estimation method
- Principles of method if other than guideline:
- The solubility of the test item in n-octanol and in water is determined. The quotient of the n-octanol solubility and the water solubility is an estimation of the Pow. The estimation method can be applied if the shake flask method and HPLC method are not applicable.
- GLP compliance:
- yes
- Type of method:
- estimation method (solubility ratio)
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Type:
- Pow
- Partition coefficient:
- < 0.003
- Temp.:
- 20 °C
- Remarks on result:
- other: pH not mentioned
- Type:
- log Pow
- Partition coefficient:
- < -2.5
- Temp.:
- 20 °C
- Remarks on result:
- other: pH not mentioned
- Conclusions:
- The estimation method was applied for the determination of the partition coefficient of MEAHA-Na.
The Pow value of the test item at 20°C was estimated at < 0.00313.
This corresponds with a log Pow value of < -2.5. - Executive summary:
The estimation method was applied for the determination of the partition coefficient of MEAHA-Na.
The Pow value of the test item at 20°C was estimated at < 0.00313.
This corresponds with a log Pow value of < -2.5.
Reference
Description of key information
The estimation method was applied for the determination of the partition coefficient of MEAHA-Na.
The Pow value of the test item at 20°C was estimated at < 0.0031.
This corresponds with a log Pow value of < -2.5.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- -2.5
- at the temperature of:
- 20 °C
Additional information
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