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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 234-766-4 | CAS number: 12032-30-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
- Endpoint:
- vapour pressure
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the melting point is above 300°C
- Justification for type of information:
READ-ACROSS
1. HYPOTHESIS FOR THE ANALOGUE APPROACH
A read-across based on analogue approach has been performed for that endpoint.
The read-across hypothesis, according to Read Across Assessment Framework published by ECHA, is based on the fact that different compounds which have the same type of effect(s). It corresponds to the scenario 2 described as follows:
« This scenario covers the analogue approach for which the read-across hypothesis is based on different compounds which have the same type of effect(s). For the REACH information requirement under consideration, the effects obtained in a study conducted with one source substance are used to predict the effects that would be observed in a study with the target substance if it were to be conducted. The same type of effect(s) or absence of effect is predicted. The predicted strength of the effects may be similar or based on a worst-case assumption. ».
2. SOURCE AND TARGET CHEMICAL(S) (INCLUDING INFORMATION ON PURITY AND IMPURITIES)
The read-across has been performed between magnesium titanate (CAS No. 12032-30-2; target chemical) and calcium titanate (CAS No. 12049-50-2; source chemical).
3. ANALOGUE APPROACH JUSTIFICATION
Both molecules share the same functional group. Therefore, they have common functional groups (Titanium trioxide) and it is expected that these molecules have also common breakdown products and common mechanisms of action.
3. ANALOGUE APPROACH JUSTIFICATION
The read-across approach is justified because both compounds have strong structural similarities and it is expected that they also have common breakdown products or mechanism of action.
Based on these elements, it can be assumed that acetone magnesium titanate and calcium titanate may have similar toxicological properties. The read-across approach between the source and the target chemicals is therefore relevant for this endpoint.
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- data waiving: supporting information
Reference
- Endpoint:
- melting point/freezing point
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- 1. HYPOTHESIS FOR THE ANALOGUE APPROACH
A read-across based on analogue approach has been performed for that endpoint.
The read-across hypothesis, according to Read Across Assessment Framework published by ECHA, is based on the fact that different compounds which have the same type of effect(s). It corresponds to the scenario 2 described as follows:
« This scenario covers the analogue approach for which the read-across hypothesis is based on different compounds which have the same type of effect(s). For the REACH information requirement under consideration, the effects obtained in a study conducted with one source substance are used to predict the effects that would be observed in a study with the target substance if it were to be conducted. The same type of effect(s) or absence of effect is predicted. The predicted strength of the effects may be similar or based on a worst-case assumption. ».
2. SOURCE AND TARGET CHEMICAL(S) (INCLUDING INFORMATION ON PURITY AND IMPURITIES)
The read-across has been performed between magnesium titanate (CAS No. 12032-30-2; target chemical) and calcium titanate (CAS No. 12049-50-2; source chemical).
3. ANALOGUE APPROACH JUSTIFICATION
Both molecules share the same functional group. Therefore, they have common functional groups (Titanium trioxide and alkaline earth metal) and it is expected that these molecules have also common breakdown products and common mechanisms of action.
3. ANALOGUE APPROACH JUSTIFICATION
The read-across approach is justified because both compounds have strong structural similarities and it is expected that they also have common breakdown products or mechanism of action.
Based on these elements, it can be assumed that acetone magnesium titanate and calcium titanate may have similar toxicological properties. The read-across approach between the source and the target chemicals is therefore relevant for this endpoint. - Reason / purpose for cross-reference:
- read-across source
- Key result
- Melting / freezing pt.:
- 1 980 °C
- Remarks on result:
- other: no information upon method
- Reason / purpose for cross-reference:
- read-across: supporting information
Reference
- Endpoint:
- melting point/freezing point
- Type of information:
- not specified
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Handbook data; no guideline stated
- Type of method:
- other: Handbook data; no guideline stated
- Key result
- Melting / freezing pt.:
- 1 980 °C
- Remarks on result:
- other: Handbook data
- Conclusions:
- The melting point of calcium titanate is 1,980°C.
- Executive summary:
The melting point of calcium titanate is 1,980°C. This figure was obtained from CRC handbook data.
Data source
Materials and methods
Results and discussion
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.